| Entry |
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| Name |
Chloramphenicol sodium succinate (JP18/USP);
Chloromycetin succinate (TN) |
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| Product |
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| Generic |
|
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| Formula |
C15H15Cl2N2O8. Na
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| Exact mass |
444.0103
|
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| Mol weight |
445.184
|
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| Structure |
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| Simcomp |
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| Class |
Antibacterial
DG01576 Amphenicol type antibacterial
|
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| Remark |
| Therapeutic category: | 6151 |
| Product (DG00399): | D00104<JP> D02185<JP/US> |
|
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| Efficacy |
Antibacterial, Antirickettsial, Protein biosynthesis inhibitor |
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| Disease |
|
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| Comment |
Amphenicol derivative
Active form of prodrug: Chloramphenicol [DR: D00104]
|
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| Target |
50S ribosomal subunit |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
D06A ANTIBIOTICS FOR TOPICAL USE
D06AX Other antibiotics for topical use
D06AX02 Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
D10 ANTI-ACNE PREPARATIONS
D10A ANTI-ACNE PREPARATIONS FOR TOPICAL USE
D10AF Antiinfectives for treatment of acne
D10AF03 Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
G GENITO URINARY SYSTEM AND SEX HORMONES
G01 GYNECOLOGICAL ANTIINFECTIVES AND ANTISEPTICS
G01A ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
G01AA Antibiotics
G01AA05 Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01B AMPHENICOLS
J01BA Amphenicols
J01BA01 Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01A ANTIINFECTIVES
S01AA Antibiotics
S01AA01 Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
S02 OTOLOGICALS
S02A ANTIINFECTIVES
S02AA Antiinfectives
S02AA01 Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
S03A ANTIINFECTIVES
S03AA Antiinfectives
S03AA08 Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
Antibacterials
Antibacterials, Other
Chloramphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
615 Acting mainly on gram-positive bacteria, gram-negative bacteria, rickettsia and chlamydia
6151 Chloramphenicols
D02185 Chloramphenicol sodium succinate (JP18/USP)
Drug groups [BR:br08330]
Antibacterial
DG01576 Amphenicol type antibacterial
DG00399 Chloramphenicol
D02185 Chloramphenicol sodium succinate
Antimicrobials [BR:br08307]
Antibacterials
Protein biosynthesis inhibitor
Amphenicol
D02185 Chloramphenicol sodium succinate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
Chemicals
D02185 Chloramphenicol sodium succinate
Drug groups [BR:br08330]
Antibacterial
DG01576 Amphenicol type antibacterial
DG00399 Chloramphenicol
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Protein biosynthesis inhibitor
Amphenicol
DG00399 Chloramphenicol
Prodrugs [br08324.html]
DG00399
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C8y C 21.3161 -15.5137
2 C1c C 21.3153 -16.9056
3 C8x C 20.1197 -14.7987
4 C8x C 22.5374 -14.8000
5 C1c C 22.5186 -17.6023
6 O1a O 20.1125 -17.5884
7 C8x C 20.1205 -13.3951
8 C8x C 22.5380 -13.3964
9 N1b N 23.7158 -16.9128
10 C8y C 21.3175 -12.7058
11 C5a C 24.9188 -17.6095
12 N2b N 21.3185 -11.3139 #+
13 C1c C 26.1289 -16.9199
14 O5a O 24.9182 -19.0013
15 O3a O 20.1220 -10.6173
16 O3a O 22.5166 -10.6070 #-
17 X Cl 27.3249 -17.6166
18 X Cl 26.0890 -15.5280
19 C1b C 22.5172 -19.0063
20 O7a O 21.3020 -19.7065
21 C7a C 21.3006 -21.1401
22 O6a O 20.0910 -21.8371
23 C1b C 22.5548 -21.8661
24 C1b C 23.7829 -21.1588
25 C6a C 24.9813 -21.8524
26 O6a O 26.1975 -21.1519 #-
27 O6a O 24.9798 -23.2741
28 Z Na 27.7330 -21.4961 #+
BOND 27
1 5 9 1
2 7 10 2
3 9 11 1
4 10 12 1
5 11 13 1
6 11 14 2
7 12 15 2
8 12 16 1
9 13 17 1
10 13 18 1
11 8 10 1
12 1 2 1
13 1 3 2
14 1 4 1
15 2 5 1
16 2 6 1 #Down
17 3 7 1
18 4 8 2
19 5 19 1
20 19 20 1
21 20 21 1
22 21 22 2
23 21 23 1
24 23 24 1
25 24 25 1
26 25 26 1
27 25 27 2
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