| Entry |
|
|---|
| Name |
Flumethiazide (INN);
Ademol (TN) |
|---|
| Formula |
C8H6F3N3O4S2
|
|---|
| Exact mass |
328.9752
|
|---|
| Mol weight |
329.2761
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Efficacy |
Antihypertensive, Na+-Cl- symport inhibitor |
|---|
| Comment |
Thiazides
|
|---|
| Target |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07017 | Sulfonamide derivatives - diuretics |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG03231 Antihypertensive
DG01749 Thiazide diuretic
D02453 Flumethiazide
DG01690 Sulfonamide diuretic
DG01749 Thiazide diuretic
D02453 Flumethiazide
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC12
SLC12A1 (NKCC2)
D02453 Flumethiazide (INN)
SLC12A3 (TSC)
D02453 Flumethiazide (INN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 20
1 C8y C 19.6068 -19.4515
2 C8y C 19.6126 -18.0526
3 C8x C 20.8125 -20.1598
4 N5x N 18.4008 -20.1539
5 C8x C 20.8242 -17.3561
6 S2x S 18.4008 -17.3502
7 C8y C 22.0299 -19.4632
8 C8x C 17.1834 -19.4515
9 C8y C 22.0359 -18.0643
10 N4x N 17.1834 -18.0526
11 O3c O 17.3883 -16.3551
12 O3c O 19.6068 -16.6478
13 C1d C 23.2358 -20.1598
14 S4a S 23.2416 -17.3502
15 X F 24.4356 -19.4515
16 X F 23.2241 -21.5587
17 X F 24.4356 -20.8622
18 N1a N 24.4474 -16.6478
19 O3c O 24.4474 -18.0526
20 O3c O 22.2408 -16.3551
BOND 21
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 2
7 4 8 2
8 5 9 2
9 6 10 1
10 6 11 2
11 6 12 2
12 7 13 1
13 9 14 1
14 13 15 1
15 13 16 1
16 13 17 1
17 14 18 1
18 14 19 2
19 14 20 2
20 7 9 1
21 8 10 1
|
|---|
