KEGG   DRUG: Cholestyramine resin
Entry
D02690                      Drug                                   
Name
Cholestyramine resin (USP);
Colestyramine (JAN/INN);
Questran (TN)
Product
  Generic
Formula
(C12H18N. Cl)n
Structure
Class
Hypolipidemic agent
 DG01946  Hypolipidemic agent
  DG01945  Bile acid sequestrant
Remark
Therapeutic category: 2189 3929
ATC code: C10AC01
Product: D02690<JP/US>
Efficacy
Antihyperlipidemic, Bile acid sequestrant, Remover (active metabolite of leflunomide)
  Disease
Hypercholesterolemia [DS:H01635]
Comment
Bile acid-binding resin, anion exchange resin
Target
Bile acid [CPD:C01558]
Interaction
Structure map
map07052  Antidyslipidemic agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C10 LIPID MODIFYING AGENTS
   C10A LIPID MODIFYING AGENTS, PLAIN
    C10AC Bile acid sequestrants
     C10AC01 Colestyramine
      D02690  Cholestyramine resin (USP) <JP/US>
USP drug classification [BR:br08302]
 Cardiovascular Agents
  Dyslipidemics, Other
   Cholestyramine
    D02690  Cholestyramine resin (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   218  Hyperlipidemia agents
    2189  Others
     D02690  Cholestyramine resin (USP); Colestyramine (JAN/INN)
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   392  Antidotes
    3929  Others
     D02690  Cholestyramine resin (USP); Colestyramine (JAN/INN)
Drug groups [BR:br08330]
 Hypolipidemic agent
  DG01946  Hypolipidemic agent
   DG01945  Bile acid sequestrant
    D02690  Cholestyramine resin
Drug classes [BR:br08332]
 Cardiovascular agent
  DG01946  Hypolipidemic agent
   D02690  Cholestyramine resin
Other DBs
CAS: 11041-12-6
PubChem: 17396859
NIKKAJI: J427.997B
LinkDB
KCF data

ATOM        16
            1   C8x C    13.0200  -12.8100
            2   C8x C    13.0200  -14.2100
            3   C8y C    14.2324  -14.9100
            4   C8x C    15.4449  -14.2100
            5   C8x C    15.4449  -12.8100
            6   C8y C    14.2324  -12.1100
            7   C1b C    14.2324  -10.7102
            8   C1a C    15.4280  -10.0198
            9   C1b C    14.2324  -16.3098
            10  N1d N    15.4280  -17.0002 #+
            11  C1a C    16.6405  -17.7002
            12  C1a C    14.7171  -18.2321
            13  C1a C    16.1165  -15.8072
            14  Z   *     9.7832   -9.5803
            15  Z   *    20.0452  -11.2652
            16  X   Cl   12.3900  -16.5200 #-
BOND        15
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     6   7 1
            8     7   8 1
            9     3   9 1
            10    9  10 1
            11   10  11 1
            12   10  12 1
            13   10  13 1
            14    7  14 1
            15    8  15 1
BRACKET     1    11.2700  -19.1800   11.2700   -9.3100
            1    18.6900   -9.3100   18.6900  -19.1800
            1  n
 ORIGINAL  1    1   2   3   4   5   6   7   8   9  10  11  12  13  16
 REPEAT    1

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