KEGG   DRUG: Menotropins
Entry
D02692                      Drug                                   
Name
Menotropins (USAN);
Human menopausal gonadotrophin (JP18);
Gonadoryl (JAN);
Humegon (TN)
Remark
Therapeutic category: 2413
ATC code: G03GA02
Chemical structure group: DG00472
Product (DG00472): D02692<JP> D06459<JP>
Efficacy
Ovulation inducing agent, Luteinizing hormone/choriogonadotropin receptor agonist, Follicle stimulating hormone receptor agonist
Comment
An extract of human post-menopausal urine containing both FSH (Follicle Stimulating Hormone; CAS 9002-68-0) and LH (Luteinising hormone; CAS 9002-67-9)
Target
LHCGR [HSA:3973] [KO:K04248]
FSHR [HSA:2492] [KO:K04247]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04913  Ovarian steroidogenesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS
    G03GA Gonadotropins
     G03GA02 Human menopausal gonadotrophin
      D02692  Menotropins (USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   241  Pituitary hormone preparations
    2413  Gonadotropic hormones
     D02692  Menotropins (USAN); Human menopausal gonadotrophin (JP18); Gonadoryl (JAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Follicle stimulating hormone
    FSHR
     D02692  Menotropins (USAN) <JP>
   Lutropin-choriogonadotropic hormone
    LHCGR
     D02692  Menotropins (USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02692  Human menopausal gonadotrophin
Other DBs
CAS: 61489-71-2
PubChem: 47205812
LinkDB

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