| Entry |
|
|---|
| Name |
Acitretin (USP/INN);
Soriatane (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C21H26O3
|
|---|
| Exact mass |
326.1882
|
|---|
| Mol weight |
326.4293
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Vitamin and mineral
DG01604 Retinol derivative
|
|---|
| Remark |
|
|---|
| Efficacy |
Antipsoriatic, Retinoic acid receptor agonist |
|---|
| Disease |
|
|---|
| Comment |
Vitamin A derivative
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Structure map |
| map07223 | Retinoic acid receptor (RAR) and retinoid X receptor (RXR) agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D05 ANTIPSORIATICS
D05B ANTIPSORIATICS FOR SYSTEMIC USE
D05BB Retinoids for treatment of psoriasis
D05BB02 Acitretin
D02754 Acitretin (USP/INN) <US>
USP drug classification [BR:br08302]
Dermatological Agents
Acne and Rosacea Agents
Retinoids
Acitretin
D02754 Acitretin (USP/INN)
Drug groups [BR:br08330]
Vitamin and mineral
DG01604 Retinol derivative
D02754 Acitretin
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Retinoic acid receptor (RAR)
NR1B (RAR)
D02754 Acitretin (USP/INN) <US>
Hepatocyte nuclear factor 4 like receptors
Retinoid X receptor (RXR)
NR2B (RXR)
D02754 Acitretin (USP/INN) <US>
|
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| Other DBs |
|
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| LinkDB |
|
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| KCF data |
ATOM 24
1 C8y C 21.1622 -16.4882
2 C8y C 21.1622 -17.8979
3 C8y C 19.9639 -15.7834
4 C2b C 22.4309 -15.7834
5 C8x C 19.9639 -18.6028
6 C8y C 18.7657 -16.4882
7 C1a C 19.9639 -14.3736
8 C2b C 23.6292 -16.4882
9 C8y C 18.7657 -17.8979
10 C2c C 24.8274 -15.7834
11 C2b C 26.0257 -16.4882
12 C1a C 24.8274 -14.3736
13 C2b C 27.2239 -15.7834
14 C2b C 28.4222 -16.4882
15 C2c C 29.6204 -15.7834
16 C2b C 30.8187 -16.4177
17 C1a C 29.6204 -14.3736
18 C6a C 32.0169 -15.7834
19 O6a O 33.2857 -16.4177
20 O6a O 32.0169 -14.3736
21 C1a C 17.5392 -15.7933
22 O2a O 17.5449 -18.6028
23 C1a C 22.4057 -18.6028
24 C1a C 16.3183 -17.9079
BOND 24
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 2
5 3 6 1
6 3 7 1
7 4 8 2
8 5 9 1
9 8 10 1
10 10 11 2
11 10 12 1
12 11 13 1
13 13 14 2
14 14 15 1
15 15 16 2
16 15 17 1
17 16 18 1
18 18 19 1
19 18 20 2
20 6 9 2
21 6 21 1
22 9 22 1
23 23 2 1
24 24 22 1
|
|---|
