| Entry |
|
|---|
| Name |
Aptiganel hydrochloride (USAN) |
|---|
| Formula |
C20H21N3. HCl
|
|---|
| Exact mass |
339.1502
|
|---|
| Mol weight |
339.8618
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
|
|---|
| Efficacy |
Stroke treatment, NMDA receptor antagonist |
|---|
| Comment |
Stroke and traumatic brain injury treatment
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01498 NMDA receptor antagonist
D02973 Aptiganel hydrochloride
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Glutamate (ionotropic), NMDA
GRIN (NMDAR)
D02973 Aptiganel hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 24
1 C8y C 12.2500 -18.2700
2 C8y C 12.2500 -19.6700
3 C8x C 13.4624 -20.3700
4 C8x C 14.6749 -19.6700
5 C8y C 14.6749 -18.2700
6 C8x C 13.4624 -17.5700
7 C8x C 11.0376 -17.5700
8 C8x C 9.8251 -18.2700
9 C8x C 9.8251 -19.6700
10 C8x C 11.0376 -20.3700
11 N2a N 17.0997 -19.6700
12 C2c C 17.0997 -18.2700
13 N1b N 15.8873 -17.5700
14 C8x C 19.5246 -19.6700
15 C8y C 19.5246 -18.2700
16 N1c N 18.3122 -17.5700
17 C8x C 20.7370 -20.3700
18 C8x C 21.9495 -19.6700
19 C8y C 21.9495 -18.2700
20 C8x C 20.7370 -17.5700
21 C1a C 24.3744 -18.2700
22 C1b C 23.1619 -17.5700
23 C1a C 18.3122 -16.1703
24 X Cl 28.9800 -19.7400
BOND 25
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 2
9 8 9 1
10 9 10 2
11 10 2 1
12 11 12 2
13 12 13 1
14 5 13 1
15 14 15 1
16 15 16 1
17 12 16 1
18 14 17 2
19 17 18 1
20 18 19 2
21 19 20 1
22 15 20 2
23 21 22 1
24 19 22 1
25 16 23 1
|
|---|
