| Entry |
|
|---|
| Name |
Cloprednol (USAN/INN);
Cloradryn (TN) |
|---|
| Formula |
C21H25ClO5
|
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| Exact mass |
392.1391
|
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| Mol weight |
392.8732
|
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
|
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| Efficacy |
Antiasthmatic, Glucocorticoid receptor agonist |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB14 Cloprednol
D03561 Cloprednol (USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
D03561 Cloprednol
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D03561 Cloprednol (USAN/INN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C1z C 26.5612 -17.3125
2 C1z C 25.3973 -17.9686
3 C1x C 27.7138 -17.9858
4 C5a C 26.5498 -15.5323
5 C1y C 25.3914 -19.3096
6 C1x C 24.2506 -17.2954
7 C1a C 25.3803 -16.6279
8 C1x C 27.7082 -19.3210
9 C1y C 24.2277 -19.9772
10 C1y C 23.0809 -17.9516
11 C1y C 23.0696 -19.2923
12 C2x C 24.2277 -21.3181
13 C1z C 21.9054 -19.9657
14 C2y C 23.0581 -21.9913
15 C2y C 21.8998 -21.3066
16 C2x C 20.7475 -19.2868
17 C1a C 21.8943 -18.6192
18 C2x C 20.7475 -21.9855
19 C2x C 19.5777 -19.9657
20 C5x C 19.5777 -21.3066
21 X Cl 23.0496 -23.3780
22 O5x O 18.3948 -21.9879
23 O1a O 21.8315 -17.2130
24 O1a O 27.8005 -16.5963
25 O5a O 25.2953 -14.8190
26 C1b C 27.7540 -14.8262
27 O1a O 28.9509 -15.5070
BOND 30
1 1 2 1
2 1 3 1
3 1 4 1 #Up
4 2 5 1
5 2 6 1
6 2 7 1 #Up
7 3 8 1
8 5 9 1
9 6 10 1
10 9 11 1
11 9 12 1
12 11 13 1
13 12 14 2
14 13 15 1
15 13 16 1
16 13 17 1 #Up
17 15 18 2
18 16 19 2
19 18 20 1
20 5 8 1
21 10 11 1
22 14 15 1
23 19 20 1
24 14 21 1
25 20 22 2 #Up
26 10 23 1 #Up
27 1 24 1 #Down
28 4 25 2
29 4 26 1
30 26 27 1
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