| Entry |
|
|---|
| Name |
Droperidol and fentanyl citrate;
Innovar (TN) |
|---|
| Formula |
C22H28N2O. C6H8O7. C22H22FN3O2
|
|---|
| Exact mass |
907.4168
|
|---|
| Mol weight |
908.0214
|
|---|
| Structure |
|
|---|
| Component |
|
|---|
| Class |
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
|
|---|
| Efficacy |
Anesthetic (intravenous) |
|---|
| Comment |
neuroleptanalgesia
Fentanyl is primarily metabolized by CYP3A4.
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N01 ANESTHETICS
N01A ANESTHETICS, GENERAL
N01AH Opioid anesthetics
N01AH51 Fentanyl, combinations
D03852 Droperidol and fentanyl citrate
Drug groups [BR:br08330]
Neuropsychiatric agent
DG02030 Anesthetics
DG02027 General anesthetics
DG02026 Opioid anesthetics
D03852 Droperidol and fentanyl citrate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
D03852 Droperidol and fentanyl citrate
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D03852
|
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| Other DBs |
|
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| LinkDB |
|
|---|
| KCF data |
ATOM 66
1 N4y N 34.5158 -10.6492
2 C8y C 35.8311 -11.0790
3 C2y C 33.3222 -11.3512
4 C8y C 34.5137 -9.2374
5 C8y C 36.7019 -9.9314
6 C8x C 36.4555 -12.3562
7 C1x C 33.3222 -12.7555
8 C2x C 32.0584 -10.6492
9 N4x N 35.8821 -8.8153
10 O5x O 33.3733 -8.4363
11 C8x C 38.0647 -10.1452
12 C8x C 37.8182 -12.5699
13 C1x C 32.0584 -13.4576
14 C1x C 30.8648 -11.3512
15 C8x C 38.6192 -11.4295
16 N1y N 30.8648 -12.7555
17 C1b C 29.6712 -13.4576
18 C1b C 28.4074 -12.7555
19 C1b C 27.2138 -13.4576
20 C5a C 26.0201 -12.7555
21 C8y C 24.7562 -13.4576
22 O5a O 26.0201 -11.3512
23 C8x C 23.5627 -12.7555
24 C8x C 24.7562 -14.8619
25 C8x C 22.3691 -13.4576
26 C8x C 23.5627 -15.5640
27 C8y C 22.3691 -14.8619
28 X F 21.1755 -15.5640
29 C8x C 18.9750 -21.2095
30 C8x C 18.9750 -22.6137
31 C8x C 20.1911 -23.3159
32 C8x C 21.4073 -22.6137
33 C8y C 21.4073 -21.2095
34 C8x C 20.1911 -20.5073
35 C1b C 22.6420 -20.4963
36 C1b C 23.8509 -21.1941
37 N1y N 25.0367 -20.5092
38 C1x C 26.2344 -21.2007
39 C1x C 27.4505 -20.4985
40 C1y C 27.4505 -19.0942
41 C1x C 26.2529 -18.4029
42 C1x C 25.0367 -19.1050
43 N1c N 28.6777 -18.3855
44 C8y C 29.8904 -19.0856
45 C8x C 29.8909 -20.5069
46 C8x C 31.1072 -21.2087
47 C8x C 32.3230 -20.5061
48 C8x C 32.3225 -19.0848
49 C8x C 31.1063 -18.3830
50 C5a C 28.6775 -16.9968
51 C1b C 27.4512 -16.2891
52 O5a O 29.8835 -16.3002
53 C1a C 26.2475 -16.9845
54 C1d C 37.9470 -19.4909
55 C1b C 36.6894 -20.1895
56 C1b C 39.1348 -20.1895
57 C6a C 38.5758 -18.3031
58 O1a O 37.2484 -18.3031
59 C6a C 35.5017 -19.4909
60 C6a C 39.1348 -21.5870
61 O6a O 37.8772 -17.1154
62 O6a O 39.9732 -18.3031
63 O6a O 34.3139 -20.1895
64 O6a O 35.5017 -18.0935
65 O6a O 40.3225 -22.2857
66 O6a O 37.8772 -22.2857
BOND 70
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 2
5 2 6 1
6 3 7 1
7 3 8 2
8 4 9 1
9 4 10 2
10 5 11 1
11 6 12 2
12 7 13 1
13 8 14 1
14 11 15 2
15 13 16 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 20 22 2
22 21 23 2
23 21 24 1
24 23 25 1
25 24 26 2
26 25 27 2
27 27 28 1
28 5 9 1
29 12 15 1
30 14 16 1
31 26 27 1
32 29 30 2
33 30 31 1
34 31 32 2
35 32 33 1
36 33 34 2
37 29 34 1
38 33 35 1
39 35 36 1
40 36 37 1
41 37 38 1
42 38 39 1
43 39 40 1
44 40 41 1
45 41 42 1
46 37 42 1
47 40 43 1
48 43 44 1
49 44 45 2
50 45 46 1
51 46 47 2
52 47 48 1
53 48 49 2
54 44 49 1
55 43 50 1
56 50 51 1
57 50 52 2
58 51 53 1
59 54 55 1
60 54 56 1
61 54 57 1
62 54 58 1
63 55 59 1
64 56 60 1
65 57 61 1
66 57 62 2
67 59 63 1
68 59 64 2
69 60 65 1
70 60 66 2
BRACKET 1 18.3400 -23.5200 18.3400 -16.0300
1 41.4400 -16.0300 41.4400 -23.5200
1 1 #GEN
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