| Entry |
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| Name |
Dopexamine hydrochloride (USAN);
Dopacard (TN) |
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| Formula |
C22H32N2O2. 2HCl
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| Exact mass |
428.1997
|
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| Mol weight |
429.4236
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| Structure |
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| Simcomp |
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| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01951 Catecholamine adrenergic receptor agonist
Neuropsychiatric agent
DG01472 Dopamine agonist
|
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| Remark |
|
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| Efficacy |
Cardiotonic, beta-Adrenergic receptor agonist, Dopamine receptor agonist |
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| Comment |
Dopamine derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA14 Dopexamine
D03892 Dopexamine hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00222 Dopexamine
D03892 Dopexamine hydrochloride
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG00222 Dopexamine
D03892 Dopexamine hydrochloride
DG01951 Catecholamine adrenergic receptor agonist
DG00222 Dopexamine
D03892 Dopexamine hydrochloride
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00222 Dopexamine
D03892 Dopexamine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D03892 Dopexamine hydrochloride (USAN)
Dopamine
DRD
D03892 Dopexamine hydrochloride (USAN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01699 Catecholamine cardiotonic
DG00222 Dopexamine
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG00222 Dopexamine
DG01951 Catecholamine adrenergic receptor agonist
DG00222 Dopexamine
Neuropsychiatric agent
DG01472 Dopamine agonist
DG00222 Dopexamine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 28
1 C8y C 8.9600 -15.5400
2 C8y C 8.9600 -16.9400
3 C8x C 10.2200 -17.6400
4 C8x C 11.4100 -16.9400
5 C8y C 11.4100 -15.5400
6 C8x C 10.2200 -14.8400
7 O1a O 7.7700 -14.8400
8 O1a O 7.7700 -17.6400
9 C1b C 12.6700 -14.8400
10 C1b C 13.8600 -15.5400
11 N1b N 15.0500 -14.8400
12 C1b C 16.2400 -15.5400
13 C1b C 17.5000 -14.8400
14 C1b C 18.6900 -15.5400
15 C1b C 19.8800 -14.8400
16 C1b C 21.0700 -15.5400
17 C1b C 22.2600 -14.8400
18 N1b N 23.4500 -15.5400
19 C1b C 24.6400 -14.8400
20 C1b C 25.9700 -15.5400
21 C8y C 27.1600 -14.8400
22 C8x C 28.3500 -15.5400
23 C8x C 29.5400 -14.8400
24 C8x C 29.5400 -13.4400
25 C8x C 28.3500 -12.7400
26 C8x C 27.1600 -13.4400
27 X Cl 22.4000 -18.6900
28 X Cl 22.4000 -18.6900
BOND 27
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 2 8 1
9 5 9 1
10 9 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 21 22 2
23 22 23 1
24 23 24 2
25 24 25 1
26 25 26 2
27 21 26 1
BRACKET 1 20.8600 -19.6000 20.8600 -17.5700
1 23.3100 -17.5700 23.3100 -19.6000
1 2
ORIGINAL 1 27
REPEAT 1 28
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