| Entry |
|
|---|
| Name |
Droloxifene (USAN/INN) |
|---|
| Formula |
C26H29NO2
|
|---|
| Exact mass |
387.2198
|
|---|
| Mol weight |
387.514
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antineoplastic
DG01585 Estrogen receptor antagonist
DG01620 Tamoxifene-type antineoplastic
Hormonal agent
DG01619 Estrogen receptor antagonist/modulator
|
|---|
| Remark |
|
|---|
| Efficacy |
Antineoplastic, Estrogen receptor agonist/antagonist |
|---|
| Comment |
Selective estrogen receptor modifier (SERM)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Drug groups [BR:br08330]
Antineoplastic
DG01585 Estrogen receptor antagonist
DG01620 Tamoxifene-type antineoplastic
DG01265 Droloxifene
D03911 Droloxifene
Hormonal agent
DG01619 Estrogen receptor antagonist/modulator
DG01265 Droloxifene
D03911 Droloxifene
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
Estrogen receptor
NR3A (ESR)
D03911 Droloxifene (USAN/INN)
Drug groups [BR:br08330]
Antineoplastic
DG01585 Estrogen receptor antagonist
DG01620 Tamoxifene-type antineoplastic
DG01265 Droloxifene
Hormonal agent
DG01619 Estrogen receptor antagonist/modulator
DG01265 Droloxifene
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 29
1 C8y C 13.7200 -21.9100
2 C8x C 13.7200 -23.3100
3 C8x C 14.9324 -24.0100
4 C8x C 16.1449 -23.3100
5 C8y C 16.1449 -21.9100
6 C8x C 14.9324 -21.2100
7 C8x C 18.5697 -23.3100
8 C8y C 18.5697 -21.9100
9 C2c C 17.3573 -21.2100
10 C8x C 19.7822 -24.0100
11 C8y C 20.9946 -23.3100
12 C8x C 20.9946 -21.9100
13 C8x C 19.7822 -21.2100
14 O1a O 12.5076 -21.2100
15 C2c C 17.3573 -19.8100
16 C8y C 18.5718 -19.1088
17 C1b C 16.1469 -19.1112
18 C1a C 14.9524 -19.8010
19 C8x C 19.7683 -19.7998
20 C8x C 20.9808 -19.0999
21 C8x C 20.9809 -17.6999
22 C8x C 19.7844 -17.0090
23 C8x C 18.5719 -17.7088
24 O2a O 22.2111 -24.0123
25 C1b C 23.4086 -23.3208
26 C1b C 24.5949 -24.0057
27 N1c N 25.7867 -23.3174
28 C1a C 26.9759 -24.0039
29 C1a C 25.7867 -21.9103
BOND 31
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 1 14 1
16 9 15 2
17 15 16 1
18 15 17 1
19 17 18 1
20 16 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 16 23 1
26 11 24 1
27 24 25 1
28 25 26 1
29 26 27 1
30 27 28 1
31 27 29 1
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