| Entry |
|
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| Name |
Ephedrine sulfate (USP);
Akovaz (TN);
Corphedra (TN);
Emerphed (TN) |
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| Product |
|
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| Generic |
EPHEDRINE SULFATE (Amneal Pharmaceuticals LLC), EPHEDRINE SULFATE (AuroMedics Pharma LLC), EPHEDRINE SULFATE (Civica), EPHEDRINE SULFATE (Civica), EPHEDRINE SULFATE (Dr. Reddy's Laboratories), EPHEDRINE SULFATE (Fresenius Kabi USA), EPHEDRINE SULFATE (Gland Pharma Limited), EPHEDRINE SULFATE (Hikma Pharmaceuticals USA), EPHEDRINE SULFATE (Lifestar Pharma LLC), EPHEDRINE SULFATE (Medical Purchasing Solutions), EPHEDRINE SULFATE (Medical Purchasing Solutions), EPHEDRINE SULFATE (Medical Purchasing Solutions), EPHEDRINE SULFATE (Medical Purchasing Solutions), EPHEDRINE SULFATE (NorthStar Rx LLC), EPHEDRINE SULFATE (Sagent Pharmaceuticals), EPHEDRINE SULFATE (Sandoz), EPHEDRINE SULFATE (Xiromed) |
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| Formula |
(C10H15NO)2. H2SO4
|
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| Exact mass |
428.1981
|
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| Mol weight |
428.5429
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG01456 Adrenergic receptor agonist
Unclassified
DG03282 Ephedrine-containing preparation
|
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| Remark |
| Product (DG00227): | D01386<JP/US> D04018<US> |
|
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| Efficacy |
Antihypotensive, Bronchodilator, Adrenergic receptor agonist |
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| Comment |
Phenethylamine derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04261 | Adrenergic signaling in cardiomyocytes |
| hsa04270 | Vascular smooth muscle contraction |
|
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| Interaction |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C01 CARDIAC THERAPY
C01C CARDIAC STIMULANTS EXCL. CARDIAC GLYCOSIDES
C01CA Adrenergic and dopaminergic agents
C01CA26 Ephedrine
D04018 Ephedrine sulfate (USP) <US>
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AA Sympathomimetics, plain
R01AA03 Ephedrine
D04018 Ephedrine sulfate (USP) <US>
R01AB Sympathomimetics, combinations excl. corticosteroids
R01AB05 Ephedrine
D04018 Ephedrine sulfate (USP) <US>
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03C ADRENERGICS FOR SYSTEMIC USE
R03CA Alpha- and beta-adrenoreceptor agonists
R03CA02 Ephedrine
D04018 Ephedrine sulfate (USP) <US>
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01F MYDRIATICS AND CYCLOPLEGICS
S01FB Sympathomimetics excl. antiglaucoma preparations
S01FB02 Ephedrine
D04018 Ephedrine sulfate (USP) <US>
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00227 Ephedrine
D04018 Ephedrine sulfate
DG01456 Adrenergic receptor agonist
DG00227 Ephedrine
D04018 Ephedrine sulfate
Unclassified
DG03282 Ephedrine-containing preparation
DG00227 Ephedrine
D04018 Ephedrine sulfate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D04018 Ephedrine sulfate (USP) <US>
ADRA2
D04018 Ephedrine sulfate (USP) <US>
ADRB
D04018 Ephedrine sulfate (USP) <US>
Rx-to-OTC switch list in the USA [br08315.html]
D04018
Drug groups [BR:br08330]
Cardiovascular agent
DG01703 Cardiotonic
DG01702 Phenethylamine cardiotonic
DG00227 Ephedrine
DG01456 Adrenergic receptor agonist
DG00227 Ephedrine
Unclassified
DG03282 Ephedrine-containing preparation
DG00227 Ephedrine
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 29
1 C8x C 4.7808 -5.6980
2 C8x C 4.7808 -7.1001
3 C8x C 5.9980 -7.8012
4 C8x C 7.2081 -7.1001
5 C8y C 7.2081 -5.6980
6 C8x C 5.9980 -4.9969
7 C1c C 8.4136 -4.9969
8 C1c C 9.6245 -5.6908
9 N1b N 10.8354 -4.9898
10 C1a C 12.0464 -5.6837
11 O1a O 8.4091 -3.5948
12 C1a C 9.6275 -7.0930
13 S4a S 18.7990 -5.6463
14 O1d O 20.1988 -5.6463
15 O1d O 17.3991 -5.6861
16 O1d O 18.8618 -7.0461
17 O1d O 18.8025 -4.2464
18 C8x C 4.7808 -5.6980
19 C8x C 5.9980 -4.9969
20 C8y C 7.2081 -5.6980
21 C1c C 8.4136 -4.9969
22 C1c C 9.6245 -5.6908
23 N1b N 10.8354 -4.9898
24 C1a C 12.0464 -5.6837
25 C1a C 9.6275 -7.0930
26 O1a O 8.4091 -3.5948
27 C8x C 7.2081 -7.1001
28 C8x C 5.9980 -7.8012
29 C8x C 4.7808 -7.1001
BOND 28
1 13 14 1
2 13 15 1
3 13 16 2
4 13 17 2
5 6 1 1
6 5 7 1
7 1 2 2
8 7 8 1
9 2 3 1
10 8 9 1
11 3 4 2
12 9 10 1
13 4 5 1
14 7 11 1 #Up
15 5 6 2
16 8 12 1 #Up
17 19 18 1
18 20 21 1
19 18 29 2
20 21 22 1
21 29 28 1
22 22 23 1
23 28 27 2
24 23 24 1
25 27 20 1
26 21 26 1 #Up
27 20 19 2
28 22 25 1 #Up
BRACKET 1 3.9900 -8.6800 3.9900 -2.7300
1 13.9300 -2.7300 13.9300 -8.6800
1 2
ORIGINAL 1 1 6 5 7 8 9 10 12 11 4 3 2
REPEAT 1 18 19 20 21 22 23 24 25 26 27 28 29
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