| Entry |
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| Name |
Fluocortin butyl (USAN) |
|---|
| Formula |
C26H35FO5
|
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| Exact mass |
446.2469
|
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| Mol weight |
446.5515
|
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
|
|---|
| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AB Corticosteroids, moderately potent (group II)
D07AB04 Fluocortin
D04217 Fluocortin butyl (USAN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00413 Fluocortin
D04217 Fluocortin butyl
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D04217 Fluocortin butyl (USAN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00413 Fluocortin
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 32
1 C2x C 22.1900 -19.8800
2 C5x C 22.1900 -21.1400
3 C2x C 23.3800 -21.8400
4 C2y C 24.5000 -21.1400
5 C1z C 24.5000 -19.8800
6 C2x C 23.3800 -19.1800
7 C1y C 25.7600 -21.8400
8 C1x C 26.9500 -21.1400
9 C1y C 26.9500 -19.8800
10 C1y C 25.7600 -19.1800
11 C1y C 28.0700 -19.1800
12 C1z C 28.0700 -17.7800
13 C1x C 26.9500 -17.0800
14 C1y C 25.7600 -17.7800
15 O5x O 21.0000 -21.8400
16 C1a C 24.5000 -18.4800
17 O1a O 24.5000 -17.0800
18 C1a C 28.0700 -16.3800
19 X F 25.7600 -23.2400
20 C1x C 30.5200 -19.1800
21 C1y C 30.5200 -17.7800
22 C1y C 29.3300 -17.0800
23 C1a C 31.7100 -17.0800
24 C5a C 29.3300 -15.5400
25 C7a C 28.0700 -14.8400
26 O5a O 30.4500 -14.8400
27 O7a O 26.8800 -15.4700
28 O6a O 28.0700 -13.4400
29 C1b C 25.6941 -14.7260
30 C1b C 24.4645 -15.3768
31 C1b C 23.2650 -14.6236
32 C1a C 22.0053 -15.2899
BOND 35
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 2 15 2
18 5 16 1 #Up
19 14 17 1 #Up
20 12 18 1 #Up
21 7 19 1 #Down
22 11 20 1
23 20 21 1
24 21 22 1
25 12 22 1
26 21 23 1 #Down
27 22 24 1 #Up
28 24 25 1
29 24 26 2
30 25 27 1
31 25 28 2
32 27 29 1
33 29 30 1
34 30 31 1
35 31 32 1
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