| Entry |
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| Name |
Fluocortolone (USAN/INN) |
|---|
| Formula |
C22H29FO4
|
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| Exact mass |
376.205
|
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| Mol weight |
376.4617
|
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
|
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
|---|
| Comment |
Prednisolone [DR: D00427] derivative
|
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| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C05 VASOPROTECTIVES
C05A AGENTS FOR TREATMENT OF HEMORRHOIDS AND ANAL FISSURES FOR TOPICAL USE
C05AA Corticosteroids
C05AA08 Fluocortolone
D04218 Fluocortolone (USAN/INN)
D DERMATOLOGICALS
D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
D07A CORTICOSTEROIDS, PLAIN
D07AC Corticosteroids, potent (group III)
D07AC05 Fluocortolone
D04218 Fluocortolone (USAN/INN)
D07X CORTICOSTEROIDS, OTHER COMBINATIONS
D07XC Corticosteroids, potent, other combinations
D07XC05 Fluocortolone
D04218 Fluocortolone (USAN/INN)
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB03 Fluocortolone
D04218 Fluocortolone (USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00295 Fluocortolone
D04218 Fluocortolone
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D04218 Fluocortolone (USAN/INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00295 Fluocortolone
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 27
1 C2x C 22.7424 -19.3415
2 C5x C 22.7424 -20.6678
3 C2x C 23.9291 -21.3658
4 C2y C 25.1158 -20.6678
5 C1z C 25.1158 -19.3415
6 C2x C 23.9291 -18.6435
7 C1y C 26.3722 -21.3658
8 C1x C 27.5589 -20.6678
9 C1y C 27.5589 -19.3415
10 C1y C 26.3722 -18.6435
11 C1y C 28.7456 -18.6435
12 C1z C 28.7456 -17.2474
13 C1x C 27.5589 -16.5494
14 C1y C 26.3722 -17.2474
15 O5x O 21.5558 -21.3658
16 C1a C 25.1158 -17.9454
17 O1a O 25.1158 -16.5494
18 C1a C 28.7456 -15.8513
19 X F 26.3722 -22.7619
20 C1x C 31.1704 -18.6435
21 C1y C 31.1704 -17.2474
22 C1y C 29.9580 -16.5474
23 C1a C 32.3790 -16.5495
24 C5a C 29.9579 -15.1200
25 O5a O 28.7470 -14.4209
26 C1b C 31.1719 -14.4191
27 O1a O 32.3682 -15.1099
BOND 30
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 2 15 2
18 5 16 1 #Up
19 14 17 1 #Up
20 12 18 1 #Up
21 7 19 1 #Down
22 11 20 1
23 20 21 1
24 21 22 1
25 12 22 1
26 21 23 1 #Down
27 22 24 1 #Up
28 24 25 2
29 24 26 1
30 26 27 1
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