| Entry |
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| Name |
Peliglitazar (USAN) |
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| Formula |
C30H30N2O7
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| Exact mass |
530.2053
|
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| Mol weight |
530.5684
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| Structure |
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| Simcomp |
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| Class |
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01732 Non-thiazolidinedione type PPAR agonist
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| Efficacy |
Antidiabetic, Antidyslipidemia, Peroxisome proliferator-activated receptor (PPAR) agonist |
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| Comment |
Treatment of Type II diabetes mellitus, mixed dyslipidemia, atherosclerosis, and metabolic syndrome
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| Target |
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| Pathway |
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| Interaction |
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| Brite |
Drug groups [BR:br08330]
Antidiabetic agent
DG01685 Insulin sensitizer
DG01795 PPAR gamma agonist
DG01732 Non-thiazolidinedione type PPAR agonist
D05397 Peliglitazar
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Thyroid hormone like receptors
Peroxisome proliferator-activated receptor (PPAR)
NR1C1 (PPARA)
D05397 Peliglitazar (USAN)
NR1C3 (PPARG)
D05397 Peliglitazar (USAN)
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 39
1 C8x C 28.4900 -15.1200
2 C8y C 28.4900 -13.7200
3 C8x C 27.3000 -13.0200
4 C8x C 26.0400 -13.7200
5 C8y C 26.0400 -15.1200
6 C8x C 27.3000 -15.8200
7 O2a O 29.6800 -13.0200
8 C1a C 30.8700 -13.7200
9 O7a O 24.8500 -15.8200
10 C7a C 23.5900 -15.1200
11 N1c N 22.4000 -15.8200
12 O6a O 23.5900 -13.7200
13 C1c C 21.2100 -15.1200
14 C1b C 22.4000 -17.2200
15 C8y C 20.0200 -15.8200
16 C1a C 21.2100 -13.7200
17 C6a C 23.6600 -17.9200
18 O6a O 24.8500 -17.2200
19 O6a O 23.6600 -19.3200
20 C8x C 18.8300 -15.1200
21 C8x C 17.6400 -15.8200
22 C8y C 17.6400 -17.2200
23 C8x C 18.8300 -17.9200
24 C8x C 20.0200 -17.2200
25 O2a O 16.3800 -17.9200
26 C1b C 15.1900 -17.2200
27 C1b C 14.0000 -17.9200
28 C8y C 12.8100 -17.2200
29 C8y C 12.8100 -15.8200
30 O2x O 11.4800 -15.4000
31 C8y C 10.6400 -16.5200
32 N5x N 11.4800 -17.6400
33 C1a C 13.9300 -14.9800
34 C8y C 9.2400 -16.5200
35 C8x C 8.5400 -15.3300
36 C8x C 7.1400 -15.3300
37 C8x C 6.4400 -16.5900
38 C8x C 7.1400 -17.7800
39 C8x C 8.5400 -17.7800
BOND 42
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 7 8 1
9 5 9 1
10 9 10 1
11 10 11 1
12 10 12 2
13 11 13 1
14 11 14 1
15 13 15 1
16 13 16 1 #Down
17 14 17 1
18 17 18 1
19 17 19 2
20 15 20 2
21 20 21 1
22 21 22 2
23 22 23 1
24 23 24 2
25 15 24 1
26 22 25 1
27 25 26 1
28 26 27 1
29 27 28 1
30 28 29 2
31 29 30 1
32 30 31 1
33 31 32 2
34 28 32 1
35 29 33 1
36 31 34 1
37 34 35 2
38 35 36 1
39 36 37 2
40 37 38 1
41 38 39 2
42 34 39 1
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