| Entry |
|
|---|
| Name |
Piroxicam betadex (USAN) |
|---|
| Formula |
(C42H70O35)5. (C15H13N3O4S)2
|
|---|
| Exact mass |
6333.9742
|
|---|
| Mol weight |
6337.6138
|
|---|
| Structure |
|
|---|
| Class |
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01910 Anti-inflammatory drug, oxicams
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
|
|---|
| Remark |
| Product (DG00752): | D00127<JP/US> |
|
|---|
| Efficacy |
Analgesic, Anti-inflammatory, Antirheumatic, COX inhibitor |
|---|
| Comment |
Oxicams
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP2C9 [HSA: 1559]
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AC Oxicams
M01AC01 Piroxicam
D05511 Piroxicam betadex (USAN)
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA07 Piroxicam
D05511 Piroxicam betadex (USAN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01B ANTIINFLAMMATORY AGENTS
S01BC Antiinflammatory agents, non-steroids
S01BC06 Piroxicam
D05511 Piroxicam betadex (USAN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01910 Anti-inflammatory drug, oxicams
DG00752 Piroxicam
D05511 Piroxicam betadex
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
DG00752 Piroxicam
D05511 Piroxicam betadex
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases (EC1)
Prostaglandin synthase
PTGS1 (COX1)
D05511 Piroxicam betadex (USAN)
PTGS2 (COX2)
D05511 Piroxicam betadex (USAN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D05511
Drug groups [BR:br08330]
Anti-inflammatory
DG01504 Nonsteroidal anti-inflammatory drug (NSAID)
DG01910 Anti-inflammatory drug, oxicams
DG00752 Piroxicam
Metabolizing enzyme substrate
DG01642 CYP2C9 substrate
DG00752 Piroxicam
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 431
1 C1y C 42.5984 -21.6427
2 C1y C 41.2126 -21.6427
3 O2x O 40.5309 -22.8232
4 C1y C 41.2125 -24.0738
5 C1y C 42.5983 -24.0040
6 C1y C 43.2799 -22.8233
7 C1y C 30.4187 -21.6430
8 C1y C 29.7279 -22.8374
9 C1y C 30.4089 -24.0185
10 C1y C 31.7722 -24.0194
11 C1y C 32.4628 -22.8249
12 O2x O 31.7819 -21.6439
13 C1y C 41.2326 -16.9043
14 C1y C 40.5511 -18.0850
15 O2x O 41.2326 -19.2657
16 C1y C 42.5960 -19.2657
17 C1y C 43.2776 -18.0850
18 C1y C 42.5960 -16.9043
19 C1y C 31.7834 -16.9043
20 C1y C 30.4201 -16.9043
21 C1y C 29.7384 -18.0850
22 C1y C 30.4201 -19.2657
23 C1y C 31.7834 -19.2657
24 O2x O 32.4651 -18.0850
25 C1y C 32.9641 -13.4962
26 C1y C 32.9641 -14.8595
27 C1y C 34.1447 -15.5412
28 O2x O 35.3255 -14.8595
29 C1y C 35.3255 -13.4962
30 C1y C 34.1447 -12.8145
31 C1b C 36.5061 -15.5412
32 C1y C 37.6867 -14.8595
33 C1y C 37.6867 -13.4962
34 O2a O 36.5061 -12.8145
35 O2x O 38.8674 -15.5412
36 C1y C 40.0481 -14.8595
37 C1y C 40.0481 -13.4962
38 C1y C 38.8674 -12.8145
39 O1a O 31.7835 -12.8145
40 O1a O 38.8674 -11.4516
41 O1a O 34.1447 -11.4515
42 O2a O 31.7835 -15.5412
43 O1a O 41.2326 -12.8123
44 O2a O 41.2326 -15.5434
45 O1a O 36.5061 -16.9044
46 O1a O 44.6202 -18.0846
47 O2a O 43.2832 -20.4554
48 O1a O 29.7442 -15.7334
49 O2a O 29.7332 -20.4548
50 O1a O 28.3972 -18.0846
51 C1b C 32.4811 -20.4743
52 C1b C 34.1447 -17.3184
53 C1b C 39.1674 -18.0853
54 O1a O 43.2722 -15.7328
55 O1a O 35.3090 -17.9907
56 O1a O 38.4955 -19.2496
57 O1a O 33.8501 -20.4746
58 O1a O 28.3970 -22.8365
59 O2a O 32.4501 -25.1949
60 O2a O 40.5352 -25.1771
61 O1a O 43.2695 -25.1671
62 C1b C 33.8503 -22.8256
63 O1a O 29.7459 -25.1659
64 C1b C 40.5451 -20.4871
65 O1a O 44.6204 -22.8235
66 O1a O 39.1675 -20.4872
67 O1a O 34.5286 -21.6523
68 C1y C 35.7902 -25.1949
69 O2x O 36.4750 -26.3807
70 C1y C 37.8384 -26.3805
71 C1y C 38.5198 -25.1998
72 C1y C 37.8350 -24.0140
73 C1y C 36.4716 -24.0141
74 O1a O 38.5172 -22.8319
75 C1b C 38.5276 -27.5749
76 O1a O 35.7736 -22.8047
77 O1a O 39.9166 -27.5744
78 C8y C 15.3404 -19.4275
79 C8y C 15.3404 -20.8045
80 C8y C 16.5296 -18.7265
81 C8x C 14.1450 -18.7454
82 S2x S 16.5421 -21.4930
83 C8x C 14.1450 -21.4992
84 C8y C 17.7313 -19.4213
85 O1a O 16.5234 -17.3684
86 C8x C 12.9684 -19.4275
87 N4y N 17.6738 -20.8107
88 O3c O 14.9899 -22.4631
89 O3c O 17.9315 -22.4130
90 C8x C 12.9684 -20.8045
91 C5a C 18.9077 -18.7329
92 C1a C 18.9203 -21.4866
93 O5a O 18.9016 -17.3747
94 N1b N 20.0916 -19.4083
95 C8y C 21.2687 -18.7205
96 N5x N 22.4462 -19.3925
97 C8x C 23.6231 -18.7047
98 C8x C 23.6160 -17.3417
99 C8x C 22.4321 -16.6661
100 C8x C 21.2553 -17.3539
101 C1y C 42.5984 -21.6427
102 C1y C 41.2126 -21.6427
103 O2x O 40.5309 -22.8232
104 C1y C 41.2125 -24.0738
105 C1y C 42.5983 -24.0040
106 C1y C 43.2799 -22.8233
107 O1a O 44.6204 -22.8235
108 O1a O 43.2695 -25.1671
109 O2a O 40.5352 -25.1771
110 C1y C 38.5198 -25.1998
111 C1y C 37.8384 -26.3805
112 O2x O 36.4750 -26.3807
113 C1y C 35.7902 -25.1949
114 C1y C 36.4716 -24.0141
115 C1y C 37.8350 -24.0140
116 O1a O 38.5172 -22.8319
117 O1a O 35.7736 -22.8047
118 O2a O 32.4501 -25.1949
119 C1y C 31.7722 -24.0194
120 C1y C 30.4089 -24.0185
121 C1y C 29.7279 -22.8374
122 C1y C 30.4187 -21.6430
123 O2x O 31.7819 -21.6439
124 C1y C 32.4628 -22.8249
125 C1b C 33.8503 -22.8256
126 O1a O 34.5286 -21.6523
127 O2a O 29.7332 -20.4548
128 C1y C 30.4201 -19.2657
129 C1y C 29.7384 -18.0850
130 C1y C 30.4201 -16.9043
131 C1y C 31.7834 -16.9043
132 O2x O 32.4651 -18.0850
133 C1y C 31.7834 -19.2657
134 C1b C 32.4811 -20.4743
135 O1a O 33.8501 -20.4746
136 O2a O 31.7835 -15.5412
137 C1y C 32.9641 -14.8595
138 C1y C 32.9641 -13.4962
139 C1y C 34.1447 -12.8145
140 C1y C 35.3255 -13.4962
141 O2x O 35.3255 -14.8595
142 C1y C 34.1447 -15.5412
143 C1b C 34.1447 -17.3184
144 O1a O 35.3090 -17.9907
145 O2a O 36.5061 -12.8145
146 C1y C 37.6867 -13.4962
147 C1y C 37.6867 -14.8595
148 C1b C 36.5061 -15.5412
149 O1a O 36.5061 -16.9044
150 O2x O 38.8674 -15.5412
151 C1y C 40.0481 -14.8595
152 C1y C 40.0481 -13.4962
153 C1y C 38.8674 -12.8145
154 O1a O 38.8674 -11.4516
155 O1a O 41.2326 -12.8123
156 O2a O 41.2326 -15.5434
157 C1y C 41.2326 -16.9043
158 C1y C 40.5511 -18.0850
159 O2x O 41.2326 -19.2657
160 C1y C 42.5960 -19.2657
161 C1y C 43.2776 -18.0850
162 C1y C 42.5960 -16.9043
163 O1a O 43.2722 -15.7328
164 O1a O 44.6202 -18.0846
165 O2a O 43.2832 -20.4554
166 C1b C 39.1674 -18.0853
167 O1a O 38.4955 -19.2496
168 O1a O 34.1447 -11.4515
169 O1a O 31.7835 -12.8145
170 O1a O 29.7442 -15.7334
171 O1a O 28.3972 -18.0846
172 O1a O 28.3970 -22.8365
173 O1a O 29.7459 -25.1659
174 C1b C 38.5276 -27.5749
175 O1a O 39.9166 -27.5744
176 C1b C 40.5451 -20.4871
177 O1a O 39.1675 -20.4872
178 C1y C 42.5984 -21.6427
179 C1y C 41.2126 -21.6427
180 O2x O 40.5309 -22.8232
181 C1y C 41.2125 -24.0738
182 C1y C 42.5983 -24.0040
183 C1y C 43.2799 -22.8233
184 O1a O 44.6204 -22.8235
185 O1a O 43.2695 -25.1671
186 O2a O 40.5352 -25.1771
187 C1y C 38.5198 -25.1998
188 C1y C 37.8384 -26.3805
189 O2x O 36.4750 -26.3807
190 C1y C 35.7902 -25.1949
191 C1y C 36.4716 -24.0141
192 C1y C 37.8350 -24.0140
193 O1a O 38.5172 -22.8319
194 O1a O 35.7736 -22.8047
195 O2a O 32.4501 -25.1949
196 C1y C 31.7722 -24.0194
197 C1y C 30.4089 -24.0185
198 C1y C 29.7279 -22.8374
199 C1y C 30.4187 -21.6430
200 O2x O 31.7819 -21.6439
201 C1y C 32.4628 -22.8249
202 C1b C 33.8503 -22.8256
203 O1a O 34.5286 -21.6523
204 O2a O 29.7332 -20.4548
205 C1y C 30.4201 -19.2657
206 C1y C 29.7384 -18.0850
207 C1y C 30.4201 -16.9043
208 C1y C 31.7834 -16.9043
209 O2x O 32.4651 -18.0850
210 C1y C 31.7834 -19.2657
211 C1b C 32.4811 -20.4743
212 O1a O 33.8501 -20.4746
213 O2a O 31.7835 -15.5412
214 C1y C 32.9641 -14.8595
215 C1y C 32.9641 -13.4962
216 C1y C 34.1447 -12.8145
217 C1y C 35.3255 -13.4962
218 O2x O 35.3255 -14.8595
219 C1y C 34.1447 -15.5412
220 C1b C 34.1447 -17.3184
221 O1a O 35.3090 -17.9907
222 O2a O 36.5061 -12.8145
223 C1y C 37.6867 -13.4962
224 C1y C 37.6867 -14.8595
225 C1b C 36.5061 -15.5412
226 O1a O 36.5061 -16.9044
227 O2x O 38.8674 -15.5412
228 C1y C 40.0481 -14.8595
229 C1y C 40.0481 -13.4962
230 C1y C 38.8674 -12.8145
231 O1a O 38.8674 -11.4516
232 O1a O 41.2326 -12.8123
233 O2a O 41.2326 -15.5434
234 C1y C 41.2326 -16.9043
235 C1y C 40.5511 -18.0850
236 O2x O 41.2326 -19.2657
237 C1y C 42.5960 -19.2657
238 C1y C 43.2776 -18.0850
239 C1y C 42.5960 -16.9043
240 O1a O 43.2722 -15.7328
241 O1a O 44.6202 -18.0846
242 O2a O 43.2832 -20.4554
243 C1b C 39.1674 -18.0853
244 O1a O 38.4955 -19.2496
245 O1a O 34.1447 -11.4515
246 O1a O 31.7835 -12.8145
247 O1a O 29.7442 -15.7334
248 O1a O 28.3972 -18.0846
249 O1a O 28.3970 -22.8365
250 O1a O 29.7459 -25.1659
251 C1b C 38.5276 -27.5749
252 O1a O 39.9166 -27.5744
253 C1b C 40.5451 -20.4871
254 O1a O 39.1675 -20.4872
255 C1y C 42.5984 -21.6427
256 C1y C 41.2126 -21.6427
257 O2x O 40.5309 -22.8232
258 C1y C 41.2125 -24.0738
259 C1y C 42.5983 -24.0040
260 C1y C 43.2799 -22.8233
261 O1a O 44.6204 -22.8235
262 O1a O 43.2695 -25.1671
263 O2a O 40.5352 -25.1771
264 C1y C 38.5198 -25.1998
265 C1y C 37.8384 -26.3805
266 O2x O 36.4750 -26.3807
267 C1y C 35.7902 -25.1949
268 C1y C 36.4716 -24.0141
269 C1y C 37.8350 -24.0140
270 O1a O 38.5172 -22.8319
271 O1a O 35.7736 -22.8047
272 O2a O 32.4501 -25.1949
273 C1y C 31.7722 -24.0194
274 C1y C 30.4089 -24.0185
275 C1y C 29.7279 -22.8374
276 C1y C 30.4187 -21.6430
277 O2x O 31.7819 -21.6439
278 C1y C 32.4628 -22.8249
279 C1b C 33.8503 -22.8256
280 O1a O 34.5286 -21.6523
281 O2a O 29.7332 -20.4548
282 C1y C 30.4201 -19.2657
283 C1y C 29.7384 -18.0850
284 C1y C 30.4201 -16.9043
285 C1y C 31.7834 -16.9043
286 O2x O 32.4651 -18.0850
287 C1y C 31.7834 -19.2657
288 C1b C 32.4811 -20.4743
289 O1a O 33.8501 -20.4746
290 O2a O 31.7835 -15.5412
291 C1y C 32.9641 -14.8595
292 C1y C 32.9641 -13.4962
293 C1y C 34.1447 -12.8145
294 C1y C 35.3255 -13.4962
295 O2x O 35.3255 -14.8595
296 C1y C 34.1447 -15.5412
297 C1b C 34.1447 -17.3184
298 O1a O 35.3090 -17.9907
299 O2a O 36.5061 -12.8145
300 C1y C 37.6867 -13.4962
301 C1y C 37.6867 -14.8595
302 C1b C 36.5061 -15.5412
303 O1a O 36.5061 -16.9044
304 O2x O 38.8674 -15.5412
305 C1y C 40.0481 -14.8595
306 C1y C 40.0481 -13.4962
307 C1y C 38.8674 -12.8145
308 O1a O 38.8674 -11.4516
309 O1a O 41.2326 -12.8123
310 O2a O 41.2326 -15.5434
311 C1y C 41.2326 -16.9043
312 C1y C 40.5511 -18.0850
313 O2x O 41.2326 -19.2657
314 C1y C 42.5960 -19.2657
315 C1y C 43.2776 -18.0850
316 C1y C 42.5960 -16.9043
317 O1a O 43.2722 -15.7328
318 O1a O 44.6202 -18.0846
319 O2a O 43.2832 -20.4554
320 C1b C 39.1674 -18.0853
321 O1a O 38.4955 -19.2496
322 O1a O 34.1447 -11.4515
323 O1a O 31.7835 -12.8145
324 O1a O 29.7442 -15.7334
325 O1a O 28.3972 -18.0846
326 O1a O 28.3970 -22.8365
327 O1a O 29.7459 -25.1659
328 C1b C 38.5276 -27.5749
329 O1a O 39.9166 -27.5744
330 C1b C 40.5451 -20.4871
331 O1a O 39.1675 -20.4872
332 C1y C 42.5984 -21.6427
333 C1y C 41.2126 -21.6427
334 O2x O 40.5309 -22.8232
335 C1y C 41.2125 -24.0738
336 C1y C 42.5983 -24.0040
337 C1y C 43.2799 -22.8233
338 O1a O 44.6204 -22.8235
339 O1a O 43.2695 -25.1671
340 O2a O 40.5352 -25.1771
341 C1y C 38.5198 -25.1998
342 C1y C 37.8384 -26.3805
343 O2x O 36.4750 -26.3807
344 C1y C 35.7902 -25.1949
345 C1y C 36.4716 -24.0141
346 C1y C 37.8350 -24.0140
347 O1a O 38.5172 -22.8319
348 O1a O 35.7736 -22.8047
349 O2a O 32.4501 -25.1949
350 C1y C 31.7722 -24.0194
351 C1y C 30.4089 -24.0185
352 C1y C 29.7279 -22.8374
353 C1y C 30.4187 -21.6430
354 O2x O 31.7819 -21.6439
355 C1y C 32.4628 -22.8249
356 C1b C 33.8503 -22.8256
357 O1a O 34.5286 -21.6523
358 O2a O 29.7332 -20.4548
359 C1y C 30.4201 -19.2657
360 C1y C 29.7384 -18.0850
361 C1y C 30.4201 -16.9043
362 C1y C 31.7834 -16.9043
363 O2x O 32.4651 -18.0850
364 C1y C 31.7834 -19.2657
365 C1b C 32.4811 -20.4743
366 O1a O 33.8501 -20.4746
367 O2a O 31.7835 -15.5412
368 C1y C 32.9641 -14.8595
369 C1y C 32.9641 -13.4962
370 C1y C 34.1447 -12.8145
371 C1y C 35.3255 -13.4962
372 O2x O 35.3255 -14.8595
373 C1y C 34.1447 -15.5412
374 C1b C 34.1447 -17.3184
375 O1a O 35.3090 -17.9907
376 O2a O 36.5061 -12.8145
377 C1y C 37.6867 -13.4962
378 C1y C 37.6867 -14.8595
379 C1b C 36.5061 -15.5412
380 O1a O 36.5061 -16.9044
381 O2x O 38.8674 -15.5412
382 C1y C 40.0481 -14.8595
383 C1y C 40.0481 -13.4962
384 C1y C 38.8674 -12.8145
385 O1a O 38.8674 -11.4516
386 O1a O 41.2326 -12.8123
387 O2a O 41.2326 -15.5434
388 C1y C 41.2326 -16.9043
389 C1y C 40.5511 -18.0850
390 O2x O 41.2326 -19.2657
391 C1y C 42.5960 -19.2657
392 C1y C 43.2776 -18.0850
393 C1y C 42.5960 -16.9043
394 O1a O 43.2722 -15.7328
395 O1a O 44.6202 -18.0846
396 O2a O 43.2832 -20.4554
397 C1b C 39.1674 -18.0853
398 O1a O 38.4955 -19.2496
399 O1a O 34.1447 -11.4515
400 O1a O 31.7835 -12.8145
401 O1a O 29.7442 -15.7334
402 O1a O 28.3972 -18.0846
403 O1a O 28.3970 -22.8365
404 O1a O 29.7459 -25.1659
405 C1b C 38.5276 -27.5749
406 O1a O 39.9166 -27.5744
407 C1b C 40.5451 -20.4871
408 O1a O 39.1675 -20.4872
409 C8y C 15.3404 -19.4275
410 C8y C 15.3404 -20.8045
411 S2x S 16.5421 -21.4930
412 N4y N 17.6738 -20.8107
413 C1a C 18.9203 -21.4866
414 C8y C 17.7313 -19.4213
415 C5a C 18.9077 -18.7329
416 O5a O 18.9016 -17.3747
417 N1b N 20.0916 -19.4083
418 C8y C 21.2687 -18.7205
419 N5x N 22.4462 -19.3925
420 C8x C 23.6231 -18.7047
421 C8x C 23.6160 -17.3417
422 C8x C 22.4321 -16.6661
423 C8x C 21.2553 -17.3539
424 C8y C 16.5296 -18.7265
425 O1a O 16.5234 -17.3684
426 O3c O 14.9899 -22.4631
427 O3c O 17.9315 -22.4130
428 C8x C 14.1450 -21.4992
429 C8x C 12.9684 -20.8045
430 C8x C 12.9684 -19.4275
431 C8x C 14.1450 -18.7454
BOND 470
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 7 8 1
8 8 9 1
9 9 10 1
10 10 11 1
11 11 12 1
12 7 12 1
13 13 14 1
14 14 15 1
15 15 16 1
16 16 17 1
17 17 18 1
18 13 18 1
19 19 20 1
20 20 21 1
21 21 22 1
22 22 23 1
23 23 24 1
24 19 24 1
25 25 26 1
26 26 27 1
27 27 28 1
28 28 29 1
29 29 30 1
30 25 30 1
31 32 31 1 #Down
32 32 33 1
33 33 34 1 #Up
34 29 34 1 #Up
35 32 35 1
36 35 36 1
37 36 37 1
38 37 38 1
39 33 38 1
40 25 39 1 #Down
41 38 40 1 #Down
42 30 41 1 #Up
43 26 42 1 #Up
44 37 43 1 #Up
45 36 44 1 #Up
46 31 45 1
47 19 42 1 #Up
48 13 44 1 #Up
49 17 46 1 #Up
50 16 47 1 #Up
51 20 48 1 #Up
52 22 49 1 #Up
53 21 50 1 #Down
54 23 51 1 #Down
55 27 52 1 #Down
56 14 53 1 #Down
57 18 54 1 #Down
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59 53 56 1
60 51 57 1
61 7 49 1 #Up
62 1 47 1 #Up
63 8 58 1 #Up
64 10 59 1 #Up
65 4 60 1 #Up
66 5 61 1 #Up
67 11 62 1 #Down
68 9 63 1 #Down
69 2 64 1 #Down
70 6 65 1 #Down
71 64 66 1
72 62 67 1
73 68 69 1
74 69 70 1
75 70 71 1
76 71 72 1
77 72 73 1
78 68 73 1
79 71 60 1 #Down
80 68 59 1 #Down
81 72 74 1 #Up
82 70 75 1 #Up
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84 75 77 1
85 101 102 1
86 102 103 1
87 103 104 1
88 104 105 1
89 105 106 1
90 101 106 1
91 122 121 1
92 121 120 1
93 120 119 1
94 119 124 1
95 124 123 1
96 122 123 1
97 157 158 1
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100 160 161 1
101 161 162 1
102 157 162 1
103 131 130 1
104 130 129 1
105 129 128 1
106 128 133 1
107 133 132 1
108 131 132 1
109 138 137 1
110 137 142 1
111 142 141 1
112 141 140 1
113 140 139 1
114 138 139 1
115 147 148 1 #Down
116 147 146 1
117 146 145 1 #Up
118 140 145 1 #Up
119 147 150 1
120 150 151 1
121 151 152 1
122 152 153 1
123 146 153 1
124 138 169 1 #Down
125 153 154 1 #Down
126 139 168 1 #Up
127 137 136 1 #Up
128 152 155 1 #Up
129 151 156 1 #Up
130 148 149 1
131 131 136 1 #Up
132 157 156 1 #Up
133 161 164 1 #Up
134 160 165 1 #Up
135 130 170 1 #Up
136 128 127 1 #Up
137 129 171 1 #Down
138 133 134 1 #Down
139 142 143 1 #Down
140 158 166 1 #Down
141 162 163 1 #Down
142 143 144 1
143 166 167 1
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145 122 127 1 #Up
146 101 165 1 #Up
147 121 172 1 #Up
148 119 118 1 #Up
149 104 109 1 #Up
150 105 108 1 #Up
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152 120 173 1 #Down
153 102 176 1 #Down
154 106 107 1 #Down
155 176 177 1
156 125 126 1
157 113 112 1
158 112 111 1
159 111 110 1
160 110 115 1
161 115 114 1
162 113 114 1
163 110 109 1 #Down
164 113 118 1 #Down
165 115 116 1 #Up
166 111 174 1 #Up
167 114 117 1 #Down
168 174 175 1
169 178 179 1
170 179 180 1
171 180 181 1
172 181 182 1
173 182 183 1
174 178 183 1
175 199 198 1
176 198 197 1
177 197 196 1
178 196 201 1
179 201 200 1
180 199 200 1
181 234 235 1
182 235 236 1
183 236 237 1
184 237 238 1
185 238 239 1
186 234 239 1
187 208 207 1
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189 206 205 1
190 205 210 1
191 210 209 1
192 208 209 1
193 215 214 1
194 214 219 1
195 219 218 1
196 218 217 1
197 217 216 1
198 215 216 1
199 224 225 1 #Down
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201 223 222 1 #Up
202 217 222 1 #Up
203 224 227 1
204 227 228 1
205 228 229 1
206 229 230 1
207 223 230 1
208 215 246 1 #Down
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211 214 213 1 #Up
212 229 232 1 #Up
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214 225 226 1
215 208 213 1 #Up
216 234 233 1 #Up
217 238 241 1 #Up
218 237 242 1 #Up
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223 219 220 1 #Down
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225 239 240 1 #Down
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250 188 251 1 #Up
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252 251 252 1
253 255 256 1
254 256 257 1
255 257 258 1
256 258 259 1
257 259 260 1
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331 264 263 1 #Down
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334 265 328 1 #Up
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429 91 93 2
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431 86 90 1
432 91 94 1
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436 78 81 1
437 79 82 1
438 79 83 1
439 80 84 2
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441 96 97 1
442 97 98 2
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444 99 100 2
445 100 95 1
446 424 425 1
447 431 430 2
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449 411 426 2
450 411 427 2
451 428 429 2
452 414 415 1
453 412 413 1
454 415 416 2
455 414 412 1
456 430 429 1
457 415 417 1
458 409 410 2
459 417 418 1
460 409 424 1
461 409 431 1
462 410 411 1
463 410 428 1
464 424 414 2
465 418 419 2
466 419 420 1
467 420 421 2
468 421 422 1
469 422 423 2
470 423 418 1
BRACKET 1 27.0200 -28.3500 27.0200 -10.9200
1 46.9700 -10.9200 46.9700 -28.3500
1 5
ORIGINAL 1 1 2 3 4 5 6 65 61 60 71 70 69 68 73 72 74
1 76 59 10 9 8 7 12 11 62 67 49 22 21 20 19 24
1 23 51 57 42 26 25 30 29 28 27 52 55 34 33 32 31
1 45 35 36 37 38 40 43 44 13 14 15 16 17 18 54 46
1 47 53 56 41 39 48 50 58 63 75 77 64 66
REPEAT 1 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116
1 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132
1 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148
1 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164
1 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180
1 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196
1 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212
1 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228
1 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244
1 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260
1 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276
1 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292
1 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308
1 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324
1 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340
1 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356
1 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372
1 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388
1 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404
1 405 406 407 408
2 12.8100 -23.3800 12.8100 -16.4500
2 24.2200 -16.4500 24.2200 -23.3800
2 2
ORIGINAL 2 78 79 82 87 92 84 91 93 94 95 96 97 98 99 100 80
2 85 88 89 83 90 86 81
REPEAT 2 409 410 411 412 413 414 415 416 417 418 419 420 421 422 423 424
2 425 426 427 428 429 430 431
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