KEGG   DRUG: Rasburicase
Entry
D05704                      Drug                                   
Name
Rasburicase (USAN/INN);
Rasburicase (genetical recombination) (JAN);
Elitek (TN)
Product
Sequence
C2H3O-SAVKAARYGK DNVRVYKVHK DEKTGVQTVY EMTVCVLLEG EIETSYTKAD
NSVIVATDSI KNTIYITAKQ NPVTPPELFG SILGTHFIEK YNHIHAAHVN IVCHRWTRMD
IDGKPHPHSF IRDSEEKRNV QVDVVEGKGI DIKSSLSGLT VLKSTNSQFW GFLRDEYTTL
KETWDRILST DVDATWQWKN FSGLQEVRSH VPKFDATWAT AREVTLKTFA EDNSASVQAT
MYKMAEQILA RQQLIETVEY SLPNKHYFEI DLSWHKGLQN TGKNAEVFAP QSDPNGLIKC
TVGRSSLKSK L
  Type
Peptide
Source
Aspergillus flavus [TAX:5059]
Remark
Therapeutic category: 3959
ATC code: V03AF07
Product: D05704<JP/US>
Efficacy
Uricolytic
Comment
urate oxidase [KO:K00365] [EC:1.7.3.3]
Rasburicase is contraindicated in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency [DS:H00668] because this can precipitate hemolytic anemia.
Treatment of malignancy-associated or chemotherapy-induced hyperuricemia
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 V VARIOUS
  V03 ALL OTHER THERAPEUTIC PRODUCTS
   V03A ALL OTHER THERAPEUTIC PRODUCTS
    V03AF Detoxifying agents for antineoplastic treatment
     V03AF07 Rasburicase
      D05704  Rasburicase (USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Antineoplastics
  Antineoplastic Adjuncts/Mitigators
   Rasburicase
    D05704  Rasburicase (USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   395  Enzyme preparations
    3959  Others
     D05704  Rasburicase (USAN/INN); Rasburicase (genetical recombination) (JAN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D05704
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D05704
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D05704
Other DBs
CAS: 134774-45-1
PubChem: 47207365
LinkDB

» Japanese version   » Back

DBGET integrated database retrieval system