| Entry |
|
|---|
| Name |
Dabuzalgron hydrochloride (USAN) |
|---|
| Formula |
C12H16ClN3O3S. HCl
|
|---|
| Exact mass |
353.0368
|
|---|
| Mol weight |
354.2527
|
|---|
| Structure |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
|
|---|
| Efficacy |
Overactive bladder agent, alpha1A-Adrenergic receptor partial agonist |
|---|
| Comment |
Treatment of stress urinary incontinence
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01448 alpha1-Adrenergic receptor agonist
D06394 Dabuzalgron hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1A
D06394 Dabuzalgron hydrochloride (USAN)
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 C8y C 12.1100 -13.8600
2 C8y C 12.1100 -15.2600
3 C8x C 13.3224 -15.9600
4 C8x C 14.5349 -15.2600
5 C8y C 14.5349 -13.8600
6 C8y C 13.3224 -13.1600
7 N1b N 10.8976 -13.1600
8 S4a S 9.7021 -13.8504
9 C1a C 8.4896 -14.5504
10 O3c O 10.4129 -15.0821
11 O3c O 9.0135 -12.6573
12 C1a C 13.3224 -11.7602
13 X Cl 10.8976 -15.9600
14 O2a O 15.7660 -13.1490
15 C1b C 16.9712 -13.8447
16 C2y C 18.1535 -13.1619
17 N2x N 18.1535 -11.7619
18 N1x N 19.4850 -13.5945
19 C1x C 20.3079 -12.4619
20 C1x C 19.4850 -11.3292
21 X Cl 22.7500 -13.8600
BOND 21
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 1
9 8 9 1
10 8 10 2
11 8 11 2
12 6 12 1
13 2 13 1
14 5 14 1
15 14 15 1
16 15 16 1
17 16 17 2
18 16 18 1
19 18 19 1
20 19 20 1
21 17 20 1
|
|---|
