| Entry |
|
|---|
| Name |
Succinylsulfathiazole (INN) |
|---|
| Formula |
C13H13N3O5S2
|
|---|
| Exact mass |
355.0297
|
|---|
| Mol weight |
355.3894
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
|
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| Remark |
|
|---|
| Efficacy |
Antibacterial, Folic acid biosynthesis inhibitor |
|---|
| Comment |
Sulfonamide
Active form of prodrug: Sulfathiazole [DR: D01047]
|
|---|
| Target |
dihydropteroate synthase [KO: K00796] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07016 | Sulfonamide derivatives - sulfa drugs |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07A INTESTINAL ANTIINFECTIVES
A07AB Sulfonamides
A07AB04 Succinylsulfathiazole
D07060 Succinylsulfathiazole (INN)
Drug groups [BR:br08330]
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
DG00088 Succinylsulfathiazole
D07060 Succinylsulfathiazole
Antimicrobials [BR:br08307]
Antibacterials
Folic acid biosynthesis inhibitor
Short-acting sulfonamide
D07060 Succinylsulfathiazole (INN)
Prodrugs [br08324.html]
D07060
Drug groups [BR:br08330]
Antibacterial
DG01787 Sulfonamide antibacterial
DG01784 Short-acting sulfonamide
DG00088 Succinylsulfathiazole
Prodrugs [br08324.html]
DG00088
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 23
1 O6a O 15.4700 -26.3200
2 C6a C 16.6824 -27.0200
3 C1b C 17.8779 -26.3296
4 O6a O 16.6825 -28.4198
5 C1b C 19.0653 -27.0151
6 C5a C 20.2565 -26.3271
7 N1b N 21.4460 -27.0138
8 O5a O 20.2565 -24.9203
9 C8y C 22.6361 -26.3265
10 C8x C 23.8262 -27.0135
11 C8x C 25.0386 -26.3134
12 C8y C 25.0385 -24.9134
13 C8x C 23.8485 -24.2264
14 C8x C 22.6361 -24.9265
15 S4a S 26.2640 -24.2056
16 N1b N 27.4721 -24.9029
17 O3c O 27.4596 -23.5151
18 C8y C 28.7135 -24.3358
19 N5x N 30.0218 -24.7704
20 C8x C 30.8394 -23.6604
21 C8x C 30.0364 -22.5398
22 S2x S 28.7226 -22.9572
23 O3c O 25.2028 -23.2908
BOND 24
1 1 2 1
2 2 3 1
3 2 4 2
4 3 5 1
5 5 6 1
6 6 7 1
7 6 8 2
8 7 9 1
9 9 10 2
10 10 11 1
11 11 12 2
12 12 13 1
13 13 14 2
14 9 14 1
15 12 15 1
16 15 16 1
17 15 17 2
18 16 18 1
19 18 19 2
20 19 20 1
21 20 21 2
22 21 22 1
23 18 22 1
24 15 23 2
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