| Entry |
|
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| Name |
Levocabastine (INN);
Livostin (TN) |
|---|
| Formula |
C26H29FN2O2
|
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| Exact mass |
420.2213
|
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| Mol weight |
420.52
|
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| Structure |
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| Simcomp |
|
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| Class |
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
|
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| Remark |
| Product (DG01035): | D01717<JP> |
|
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| Efficacy |
Antiallergic, H1 receptor antagonist |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
| map07212 | Histamine H1 receptor antagonists |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AC Antiallergic agents, excl. corticosteroids
R01AC02 Levocabastine
D08117 Levocabastine (INN)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01G DECONGESTANTS AND ANTIALLERGICS
S01GX Other antiallergics
S01GX02 Levocabastine
D08117 Levocabastine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01035 Levocabastine
D08117 Levocabastine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH1
D08117 Levocabastine (INN)
Drug groups [BR:br08330]
Anti-allergic agent
DG01557 Histamine receptor antagonist
DG01482 Histamine receptor H1 antagonist
DG01035 Levocabastine
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 C8y C 19.4600 -17.7100
2 C8x C 18.0600 -17.7100
3 C8x C 17.3600 -18.9000
4 C8y C 18.0600 -20.0900
5 C8x C 19.4600 -20.0900
6 C8x C 20.1600 -18.9000
7 C8y C 28.8400 -17.7100
8 C8x C 28.1400 -18.9700
9 C8x C 28.8400 -20.1600
10 C8x C 30.2400 -20.1600
11 C8x C 30.9400 -18.9700
12 C8x C 30.2400 -17.7800
13 C1z C 20.7200 -17.0100
14 C1x C 21.4200 -18.2700
15 C1x C 22.7500 -18.2700
16 C1y C 23.4500 -17.0100
17 C1x C 22.7500 -15.7500
18 C1x C 21.4200 -15.7500
19 N1y N 24.8500 -17.0100
20 C1x C 25.5500 -18.2000
21 C1x C 26.9500 -18.2000
22 C1z C 27.6500 -17.0800
23 C1y C 26.9500 -15.7500
24 C1x C 25.5500 -15.7500
25 C6a C 28.8400 -16.3100
26 C3b C 19.4600 -16.3100
27 O6a O 29.5400 -15.1200
28 O6a O 30.1700 -16.7300
29 X F 17.3600 -21.2800
30 N3a N 18.2700 -15.6100
31 C1a C 27.6500 -14.5600
BOND 34
1 13 14 1
2 14 15 1
3 15 16 1
4 16 17 1
5 17 18 1
6 18 13 1
7 5 6 2
8 7 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 11 12 2
13 19 20 1
14 20 21 1
15 21 22 1
16 22 23 1
17 23 24 1
18 24 19 1
19 16 19 1 #Up
20 12 7 1
21 22 25 1 #Down
22 6 1 1
23 13 26 1 #Up
24 13 1 1 #Down
25 22 7 1 #Up
26 1 2 2
27 25 27 2
28 2 3 1
29 25 28 1
30 3 4 2
31 4 29 1
32 4 5 1
33 26 30 3
34 23 31 1 #Up
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