| Entry |
|
|---|
| Name |
Lisuride (INN) |
|---|
| Formula |
C20H26N4O
|
|---|
| Exact mass |
338.2107
|
|---|
| Mol weight |
338.4466
|
|---|
| Structure |
|
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| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG01964 Ergot alkaloid
DG01982 Antimigraine, ergot alkaloid
|
|---|
| Remark |
|
|---|
| Efficacy |
Antimigraine, Dopamine receptor agonist |
|---|
| Comment |
Ergot alkaloid
Prolactin inhibitor
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07211 | Serotonin receptor agonists/antagonists |
| map07213 | Dopamine receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G02 OTHER GYNECOLOGICALS
G02C OTHER GYNECOLOGICALS
G02CB Prolactine inhibitors
G02CB02 Lisuride
D08132 Lisuride (INN)
N NERVOUS SYSTEM
N02 ANALGESICS
N02C ANTIMIGRAINE PREPARATIONS
N02CA Ergot alkaloids
N02CA07 Lisuride
D08132 Lisuride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG00453 Lisuride
D08132 Lisuride
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG00453 Lisuride
D08132 Lisuride
DG01964 Ergot alkaloid
DG01982 Antimigraine, ergot alkaloid
DG00453 Lisuride
D08132 Lisuride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Dopamine
DRD2
D08132 Lisuride (INN)
DRD3
D08132 Lisuride (INN)
DRD4
D08132 Lisuride (INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01483 5-HT1A-receptor agonist
DG00453 Lisuride
DG01472 Dopamine agonist
DG01468 Dopamine D2-receptor agonist
DG00453 Lisuride
DG01964 Ergot alkaloid
DG01982 Antimigraine, ergot alkaloid
DG00453 Lisuride
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 25
1 C8x C 21.6050 -19.7151
2 C8x C 21.6050 -21.0434
3 C8x C 22.7935 -19.0160
4 C8y C 23.9819 -19.7151
5 C1x C 26.3589 -21.0434
6 C2y C 25.1704 -19.0160
7 C1y C 26.3589 -19.7151
8 N1y N 27.5473 -19.0160
9 C1y C 26.3589 -16.9886
10 C2x C 25.1705 -17.6178
11 C8y C 23.9819 -21.0434
12 C8y C 22.7935 -21.7425
13 N4x N 22.7935 -23.1407
14 C8x C 25.1704 -23.1408
15 C8y C 25.1704 -21.7425
16 N1b N 26.3589 -15.5904
17 C5a C 27.5473 -14.9612
18 N1c N 28.7358 -15.6603
19 C1b C 29.9243 -14.9612
20 C1a C 28.6659 -19.7151
21 C1b C 28.7358 -16.9886
22 C1x C 27.5473 -17.6877
23 C1a C 29.9243 -17.6877
24 C1a C 31.1127 -15.6603
25 O5a O 27.5473 -13.5630
BOND 28
1 10 6 2
2 4 11 1
3 15 5 1
4 5 7 1
5 6 4 1
6 11 12 2
7 12 13 1
8 14 15 2
9 15 11 1
10 13 14 1
11 1 2 2
12 9 16 1 #Down
13 2 12 1
14 19 24 1
15 16 17 1
16 4 3 2
17 3 1 1
18 17 18 1
19 18 19 1
20 6 7 1
21 8 20 1
22 7 8 1
23 18 21 1
24 8 22 1
25 22 9 1
26 21 23 1
27 9 10 1
28 17 25 2
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