| Entry |
|
|---|
| Name |
Procaterol (INN);
Meptin (TN) |
|---|
| Formula |
C16H22N2O3
|
|---|
| Exact mass |
290.163
|
|---|
| Mol weight |
290.3575
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
| Product (DG01055): | D05366<JP> |
|
|---|
| Efficacy |
Bronchodilator, beta2-Adrenergic receptor agonist |
|---|
| Comment |
Phenethylamine derivative
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07214 | beta-Adrenergic receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03A ADRENERGICS, INHALANTS
R03AC Selective beta-2-adrenoreceptor agonists
R03AC16 Procaterol
D08424 Procaterol (INN)
R03C ADRENERGICS FOR SYSTEMIC USE
R03CC Selective beta-2-adrenoreceptor agonists
R03CC08 Procaterol
D08424 Procaterol (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01055 Procaterol
D08424 Procaterol
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01055 Procaterol
D08424 Procaterol
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRB2
D08424 Procaterol (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08424
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01455 beta-Adrenergic receptor agonist
DG01452 beta2-Adrenergic receptor agonist
DG01055 Procaterol
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01055 Procaterol
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 21
1 C8y C 20.5100 -16.1700
2 C8y C 20.5100 -17.5700
3 C8y C 21.7000 -18.2700
4 C8y C 22.9600 -17.5700
5 C8x C 22.9600 -16.1700
6 C8x C 21.7000 -15.4700
7 N4x N 19.3200 -18.2700
8 C8y C 19.3200 -19.6700
9 C8x C 20.5100 -20.3700
10 C8x C 21.7000 -19.6700
11 C1c C 24.1500 -18.2700
12 C1c C 25.4100 -17.5700
13 N1b N 26.6000 -18.2700
14 C1c C 27.7900 -17.5700
15 C1a C 29.0500 -18.2700
16 O1a O 24.1500 -19.6700
17 C1b C 25.4100 -16.1700
18 C1a C 27.7900 -16.1700
19 C1a C 24.1500 -15.4700
20 O1a O 19.3200 -15.4700
21 O5x O 18.1300 -20.3700
BOND 22
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 2 7 1
8 7 8 1
9 8 9 1
10 9 10 2
11 3 10 1
12 4 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 11 16 1
18 12 17 1
19 14 18 1
20 17 19 1
21 1 20 1
22 8 21 2
|
|---|
