KEGG   DRUG: Rifamycin sodium
Entry
D08480                      Drug                                   
Name
Rifamycin sodium (USAN);
Rifamycin SV sodium salt;
Aemcolo (TN);
Otofa (TN);
Rifocina (TN)
Product
AEMCOLO (RedHill Biopharma)
Formula
C37H47NO12. Na
Exact mass
720.2996
Mol weight
720.7583
Structure
Simcomp
Class
Antibacterial
 DG01966  Antitubercular
  DG01598  Rifamycin antibiotic
Remark
ATC code: A07AA13 D06AX15 J04AB03 S01AA16 S02AA12
Chemical structure group: DG00640
Product (DG00640): D08480<US>
Efficacy
Antibacterial (tuberculostatic)
Comment
Rifamycin derivative
Treatment of traveler's diarrhea
Interaction
Structure map
map07023  Rifamycins
map07114  Naphthalene family
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA13 Rifamycin
      D08480  Rifamycin sodium (USAN) <US>
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX15 Rifamycin
      D08480  Rifamycin sodium (USAN) <US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J04 ANTIMYCOBACTERIALS
   J04A DRUGS FOR TREATMENT OF TUBERCULOSIS
    J04AB Antibiotics
     J04AB03 Rifamycin
      D08480  Rifamycin sodium (USAN) <US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA16 Rifamycin
      D08480  Rifamycin sodium (USAN) <US>
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA12 Rifamycin
      D08480  Rifamycin sodium (USAN) <US>
USP drug classification [BR:br08302]
 Gastrointestinal Agents
  Anti-diarrheal Agents
   Rifamycin
    D08480  Rifamycin sodium (USAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01966  Antitubercular
   DG01598  Rifamycin antibiotic
    DG00640  Rifamycin
     D08480  Rifamycin sodium
Antimicrobials [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   Rifamycin
    D08480  Rifamycin sodium (USAN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D08480
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D08480
Drug groups [BR:br08330]
 Antibacterial
  DG01966  Antitubercular
   DG01598  Rifamycin antibiotic
    DG00640  Rifamycin
Other DBs
CAS: 14897-39-3
PubChem: 96025166
LigandBox: D08480
LinkDB
KCF data

ATOM        51
            1   C1c C    22.4000  -14.4200
            2   C1c C    22.4000  -15.8200
            3   O1a O    24.7800  -15.7500
            4   C1c C    24.7800  -14.4200
            5   C1c C    23.5900  -13.7200
            6   C2b C    27.0900  -14.4200
            7   C1c C    25.9000  -13.7200
            8   C5a C    28.2800  -16.5200
            9   C2c C    29.4700  -15.8200
            10  C2b C    29.4700  -14.4200
            11  C2b C    28.2800  -13.7200
            12  C1a C    25.9000  -12.3900
            13  C1a C    23.5900  -12.3900
            14  O1a O    21.2800  -13.7200
            15  C1a C    30.5900  -16.5200
            16  O5a O    27.1600  -15.8200
            17  N1b N    28.2800  -18.1300
            18  C1c C    21.2800  -16.5200
            19  O7a O    20.1600  -15.8200
            20  C1c C    21.2800  -18.1300
            21  C8y C    27.1600  -18.7600
            22  C8x C    27.1600  -20.1600
            23  C8y C    25.9000  -18.1300
            24  C8y C    24.7800  -18.7600
            25  C8y C    24.7800  -20.1600
            26  C8y C    25.9000  -20.7900
            27  C8y C    23.6600  -18.1300
            28  C8y C    22.4000  -18.7600
            29  C8y C    22.4000  -20.1600
            30  C8y C    23.6600  -20.7900
            31  O1a O    25.9000  -16.7300
            32  O1a O    23.6600  -16.7300
            33  C1a C    21.2800  -14.7700
            34  C7a C    18.9000  -15.1200
            35  C1a C    17.7800  -15.8200
            36  O6a O    18.9000  -13.7900
            37  C1c C    20.1600  -18.7600
            38  O2a O    18.9700  -18.1300
            39  C2b C    20.1600  -20.1600
            40  C1a C    20.1600  -17.1500
            41  C1a C    17.8500  -18.7600
            42  C2b C    18.9700  -20.7900
            43  O2a O    18.9700  -22.1200
            44  O2x O    21.2800  -20.7900
            45  C1z C    21.2800  -22.1200
            46  C5x C    23.6600  -22.1200
            47  C1a C    21.2800  -23.5200
            48  C1a C    22.4000  -17.4300
            49  O1a O    25.9000  -22.1200
            50  O5x O    24.7100  -22.8200
            51  Z   Na   31.6400  -20.7200
BOND        53
            1     1   2 1
            2     4   3 1 #Down
            3     4   5 1
            4     1   5 1
            5     6   7 1
            6     4   7 1
            7     8   9 1
            8     9  10 2
            9    10  11 1
            10    6  11 2
            11    7  12 1 #Up
            12    5  13 1 #Down
            13    1  14 1 #Down
            14    9  15 1
            15    8  16 2
            16    8  17 1
            17    2  18 1
            18   18  19 1 #Up
            19   18  20 1
            20   17  21 1
            21   21  22 1
            22   21  23 2
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   24  27 2
            27   27  28 1
            28   28  29 2
            29   29  30 1
            30   25  30 2
            31   23  31 1
            32   27  32 1
            33    2  33 1 #Up
            34   19  34 1
            35   34  35 1
            36   34  36 2
            37   26  22 2
            38   20  37 1
            39   37  38 1 #Down
            40   37  39 1
            41   20  40 1 #Down
            42   38  41 1
            43   39  42 2
            44   42  43 1
            45   29  44 1
            46   44  45 1
            47   43  45 1
            48   30  46 1
            49   45  46 1
            50   45  47 1 #Down
            51   28  48 1
            52   26  49 1
            53   50  46 2

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