| Entry |
|
|---|
| Name |
Roxatidine (INN);
Roxit (TN) |
|---|
| Formula |
C17H26N2O3
|
|---|
| Exact mass |
306.1943
|
|---|
| Mol weight |
306.3999
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
|
|---|
| Remark |
| Product (DG00019): | D01467<JP> |
|
|---|
| Efficacy |
Anti-ulcerative, H2 receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07227 | Histamine H2/H3 receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BA H2-receptor antagonists
A02BA06 Roxatidine
D08494 Roxatidine (INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
DG00019 Roxatidine
D08494 Roxatidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
HRH2
D08494 Roxatidine (INN)
Drug groups [BR:br08330]
Gastrointestinal agent
DG01975 Agents for peptic ulcer
DG01481 Histamine receptor H2 antagonist
DG00019 Roxatidine
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 22
1 N1b N 28.7000 -23.9400
2 C8x C 20.1600 -21.8400
3 C8y C 20.1600 -23.2400
4 C8x C 21.4200 -23.9400
5 C8y C 22.6100 -23.2400
6 C8x C 22.6100 -21.8400
7 C8x C 21.4200 -21.1400
8 O2a O 23.8700 -23.9400
9 C1b C 25.0600 -23.2400
10 C1b C 26.2500 -23.9400
11 C1b C 27.4400 -23.2400
12 C1b C 18.9700 -23.9400
13 N1y N 17.7800 -23.2400
14 C1x C 17.7800 -21.8400
15 C1x C 16.5900 -21.1400
16 C1x C 15.3300 -21.8400
17 C1x C 15.3300 -23.2400
18 C1x C 16.5200 -23.9400
19 C5a C 29.8900 -23.2400
20 C1b C 31.0800 -23.9400
21 O1a O 32.2700 -23.2400
22 O5a O 29.8900 -21.8400
BOND 23
1 6 7 2
2 7 2 1
3 13 18 1
4 14 15 1
5 15 16 1
6 16 17 1
7 17 18 1
8 8 9 1
9 9 10 1
10 2 3 2
11 10 11 1
12 11 1 1
13 8 5 1
14 1 19 1
15 19 20 1
16 3 4 1
17 20 21 1
18 3 12 1
19 4 5 2
20 12 13 1
21 19 22 2
22 13 14 1
23 5 6 1
|
|---|
