| Entry |
|
|---|
| Name |
Sarpogrelate (INN) |
|---|
| Formula |
C24H31NO6
|
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| Exact mass |
429.2151
|
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| Mol weight |
429.506
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Product (DG01333): | D01624<JP> |
|
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| Efficacy |
Anticoagulant, Platelet aggregation inhibitor, Serotonin 5-HT2 receptor antagonist |
|---|
| Target |
|
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Metabolism |
Enzyme: CYP1A2 [HSA: 1544], CYP2B6 [HSA: 1555], CYP2C9 [HSA: 1559], CYP2C19 [HSA: 1557], CYP2D6 [HSA: 1565], CYP3A4 [HSA: 1576]
|
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| Interaction |
|
|---|
| Structure map |
| map07211 | Serotonin receptor agonists/antagonists |
|
|---|
| Brite |
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG01333 Sarpogrelate
D08508 Sarpogrelate
Metabolizing enzyme substrate
DG01892 CYP1A2 substrate
DG01333 Sarpogrelate
D08508 Sarpogrelate
DG02919 CYP2B6 substrate
DG01333 Sarpogrelate
D08508 Sarpogrelate
DG01642 CYP2C9 substrate
DG01333 Sarpogrelate
D08508 Sarpogrelate
DG01639 CYP2C19 substrate
DG01333 Sarpogrelate
D08508 Sarpogrelate
DG01644 CYP2D6 substrate
DG01333 Sarpogrelate
D08508 Sarpogrelate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01333 Sarpogrelate
D08508 Sarpogrelate
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Serotonin
HTR2A
D08508 Sarpogrelate (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08508
Drug groups [BR:br08330]
Blood modifier agent
DG01950 Antithrombotic agent
DG01712 Antiplatelet agent
DG01333 Sarpogrelate
Metabolizing enzyme substrate
DG01892 CYP1A2 substrate
DG01333 Sarpogrelate
DG02919 CYP2B6 substrate
DG01333 Sarpogrelate
DG01642 CYP2C9 substrate
DG01333 Sarpogrelate
DG01639 CYP2C19 substrate
DG01333 Sarpogrelate
DG01644 CYP2D6 substrate
DG01333 Sarpogrelate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01333 Sarpogrelate
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 31
1 C8y C 19.9500 -17.9900
2 O2a O 21.1400 -17.2900
3 C8x C 18.7600 -17.2900
4 C8y C 19.9500 -19.3900
5 C1b C 22.3300 -17.9900
6 C8x C 17.5000 -17.9900
7 C8x C 18.7600 -20.0900
8 C1c C 23.5900 -17.2900
9 C8x C 17.5000 -19.3900
10 O7a O 24.7800 -17.9900
11 C1b C 23.5900 -15.8900
12 C7a C 25.9700 -17.2900
13 C1b C 27.2300 -17.9900
14 C1b C 28.4200 -17.2900
15 C6a C 29.6100 -17.9900
16 O6a O 30.8700 -17.2900
17 O6a O 25.9700 -15.8900
18 O6a O 29.6100 -19.3900
19 C1b C 21.1400 -20.0900
20 C1b C 22.3300 -19.3900
21 C8y C 23.5900 -20.0200
22 C8x C 23.5900 -21.4200
23 C8x C 24.7800 -22.1200
24 C8x C 25.9700 -21.4200
25 C8y C 25.9700 -20.0200
26 C8x C 24.7800 -19.3200
27 O2a O 27.2300 -19.3200
28 C1a C 28.4200 -20.0200
29 N1c N 22.3300 -15.1900
30 C1a C 22.3300 -13.7900
31 C1a C 21.1400 -15.8900
BOND 32
1 15 16 1
2 7 9 1
3 12 17 2
4 15 18 2
5 1 2 1
6 4 19 1
7 1 3 2
8 19 20 1
9 1 4 1
10 20 21 1
11 2 5 1
12 3 6 1
13 4 7 2
14 5 8 1
15 6 9 2
16 21 22 2
17 22 23 1
18 23 24 2
19 24 25 1
20 25 26 2
21 26 21 1
22 8 10 1
23 25 27 1
24 8 11 1
25 27 28 1
26 10 12 1
27 11 29 1
28 12 13 1
29 29 30 1
30 13 14 1
31 29 31 1
32 14 15 1
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