| Entry |
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| Name |
Tixocortol (INN) |
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| Formula |
C21H30O4S
|
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| Exact mass |
378.1865
|
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| Mol weight |
378.5255
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| Structure |
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| Simcomp |
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| Class |
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| Remark |
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| Efficacy |
Anti-inflammatory, Glucocorticoid receptor agonist |
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| Target |
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| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
A07E INTESTINAL ANTIINFLAMMATORY AGENTS
A07EA Corticosteroids acting locally
A07EA05 Tixocortol
D08610 Tixocortol (INN)
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AD Corticosteroids
R01AD07 Tixocortol
D08610 Tixocortol (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00096 Tixocortol
D08610 Tixocortol
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D08610 Tixocortol (INN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00096 Tixocortol
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 26
1 C1x C 14.4678 -17.5792
2 C5x C 14.4678 -18.9494
3 C2x C 15.6544 -19.6345
4 C2y C 16.8411 -18.9494
5 C1z C 16.8411 -17.5792
6 C1x C 15.6544 -16.8941
7 C1x C 18.0277 -19.6345
8 C1x C 19.2143 -18.9494
9 C1y C 19.2143 -17.5792
10 C1y C 18.0277 -16.8941
11 C1y C 20.4011 -16.8941
12 C1z C 20.4011 -15.5238
13 C1x C 19.2143 -14.8387
14 C1y C 18.0277 -15.5238
15 C1x C 22.7743 -16.8941
16 C1x C 22.7743 -15.5238
17 C1z C 21.5877 -14.8387
18 O5x O 13.2812 -19.6345
19 C5a C 21.5877 -13.4685
20 C1b C 22.7783 -12.7811
21 O5a O 20.4050 -12.7856
22 S1a S 23.9503 -13.4579
23 O1a O 22.7743 -14.2906
24 O1a O 16.8411 -14.8387
25 C1a C 16.8411 -16.2089
26 C1a C 20.4011 -14.1238
BOND 29
1 1 2 1
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 2 18 2
22 17 19 1 #Up
23 19 20 1
24 19 21 2
25 20 22 1
26 17 23 1 #Down
27 14 24 1 #Up
28 5 25 1 #Up
29 12 26 1 #Up
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