| Entry |
|
|---|
| Name |
Teneligliptin (INN) |
|---|
| Formula |
C22H30N6OS
|
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| Exact mass |
426.2202
|
|---|
| Mol weight |
426.5782
|
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| Structure |
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| Class |
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| Remark |
| Product (DG01283): | D09756<JP> |
| Product (mixture): | D10897<JP> |
|
|---|
| Efficacy |
Antidiabetic, Dipeptidyl peptidase-4 (DPP-4) inhibitor |
|---|
| Target |
|
|---|
| Pathway |
| hsa04974 | Protein digestion and absorption |
|
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| Metabolism |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A10 DRUGS USED IN DIABETES
A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
A10BH Dipeptidyl peptidase 4 (DPP-4) inhibitors
A10BH08 Teneligliptin
D08616 Teneligliptin (INN)
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01601 DPP-4 inhibitor
DG01283 Teneligliptin
D08616 Teneligliptin
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01283 Teneligliptin
D08616 Teneligliptin
Metabolizing enzyme inhibitor
DG01645 CYP2D6 inhibitor
DG01283 Teneligliptin
D08616 Teneligliptin
DG02852 CYP3A/CYP3A4 inhibitor
DG01522 CYP3A4 inhibitor
DG01283 Teneligliptin
D08616 Teneligliptin
DG02951 FMO inhibitor
DG01283 Teneligliptin
D08616 Teneligliptin
Unclassified
DG03306 FMO substrate
DG03191 FMO1 substrate
DG01283 Teneligliptin
D08616 Teneligliptin
DG02950 FMO3 substrate
DG01283 Teneligliptin
D08616 Teneligliptin
Target-based classification of drugs [BR:br08310]
Enzymes
Hydrolases (EC3)
Peptidyl-peptidases
DPP4 (CD26)
D08616 Teneligliptin (INN)
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D08616
Drug groups [BR:br08330]
Antidiabetic agent
DG02044 Hypoglycemic agent
DG01601 DPP-4 inhibitor
DG01283 Teneligliptin
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG01283 Teneligliptin
Metabolizing enzyme inhibitor
DG01645 CYP2D6 inhibitor
DG01283 Teneligliptin
DG02852 CYP3A/CYP3A4 inhibitor
DG01522 CYP3A4 inhibitor
DG01283 Teneligliptin
DG02951 FMO inhibitor
DG01283 Teneligliptin
Unclassified
DG03306 FMO substrate
DG03191 FMO1 substrate
DG01283 Teneligliptin
DG02950 FMO3 substrate
DG01283 Teneligliptin
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 30
1 C1x C 15.6800 -16.5900
2 N1y N 15.6800 -17.9900
3 C1x C 16.8700 -18.6900
4 C1x C 18.1300 -17.9900
5 N1y N 18.1300 -16.5900
6 C1x C 16.8700 -15.8900
7 C8y C 14.4900 -18.6900
8 C1y C 19.3200 -15.8900
9 N4y N 13.3000 -17.9200
10 N5x N 12.2500 -18.7600
11 C8y C 12.6700 -20.0200
12 C8x C 14.0700 -20.0200
13 C1a C 11.9000 -21.2100
14 C8y C 13.3000 -16.5200
15 C8x C 14.4900 -15.8200
16 C8x C 14.4900 -14.4200
17 C8x C 13.2300 -13.7200
18 C8x C 12.0400 -14.4200
19 C8x C 12.0400 -15.8200
20 C1x C 20.4400 -16.6600
21 C1y C 21.5600 -15.8900
22 N1x N 21.1400 -14.5600
23 C1x C 19.7400 -14.5600
24 C5a C 22.7500 -16.5900
25 N1y N 23.9400 -15.8900
26 O5a O 22.7500 -17.9900
27 C1x C 25.0612 -16.7284
28 S2x S 26.2050 -15.9211
29 C1x C 25.7907 -14.5838
30 C1x C 24.3909 -14.5646
BOND 34
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 5 6 1
6 1 6 1
7 2 7 1
8 8 5 1 #Down
9 7 9 1
10 9 10 1
11 10 11 2
12 11 12 1
13 7 12 2
14 11 13 1
15 9 14 1
16 14 15 2
17 15 16 1
18 16 17 2
19 17 18 1
20 18 19 2
21 14 19 1
22 8 20 1
23 20 21 1
24 21 22 1
25 22 23 1
26 8 23 1
27 21 24 1 #Down
28 24 25 1
29 24 26 2
30 25 27 1
31 27 28 1
32 28 29 1
33 29 30 1
34 25 30 1
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