| Entry |
|
|---|
| Name |
Valaciclovir (INN);
Valacyclovir;
Valtrex (TN) |
|---|
| Formula |
C13H20N6O4
|
|---|
| Exact mass |
324.1546
|
|---|
| Mol weight |
324.3357
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Antiviral
DG02840 Anti-herpesvirus agent
|
|---|
| Remark |
| Product (DG00647): | D00398<JP/US> D10518<JP/US> |
|
|---|
| Efficacy |
Antiviral, DNA polymerase inhibitor |
|---|
| Comment |
Active form of prodrug: Aciclovir [DR: D00222]
|
|---|
| Target |
Herpesvirus DNA polymerase [KO: K18964] |
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Structure map |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J05 ANTIVIRALS FOR SYSTEMIC USE
J05A DIRECT ACTING ANTIVIRALS
J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
J05AB11 Valaciclovir
D08664 Valaciclovir (INN)
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
DG00647 Valaciclovir
D08664 Valaciclovir
Antimicrobials [BR:br08307]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
D08664 Valaciclovir (INN)
Prodrugs [br08324.html]
D08664
Drug groups [BR:br08330]
Antiviral
DG02840 Anti-herpesvirus agent
DG00647 Valaciclovir
Antimicrobials abbreviations [BR:br08327]
Antivirals
Genome replication inhibitor
Herpesvirus DNA polymerase inhibitor
DG00647 Valaciclovir
Prodrugs [br08324.html]
DG00647
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 23
1 N4y N 23.8700 -17.9200
2 C8y C 25.1300 -17.4300
3 C8y C 25.1300 -16.0300
4 N5x N 23.8000 -15.6800
5 C8x C 23.0300 -16.8000
6 N5x N 26.3900 -18.1300
7 C8y C 27.5800 -17.4300
8 N4x N 27.5800 -16.0300
9 C8y C 26.3200 -15.3300
10 O5x O 26.3200 -13.9300
11 N1a N 28.8400 -18.0600
12 C1b C 23.8700 -19.3200
13 O2a O 22.6100 -20.0200
14 C1b C 21.4200 -19.3200
15 C1b C 20.1600 -20.0200
16 O7a O 18.9700 -19.3200
17 C7a C 17.7519 -20.0101
18 C1c C 16.5705 -19.3150
19 C1c C 15.3651 -19.9980
20 C1a C 14.1939 -19.3091
21 C1a C 15.4231 -21.4192
22 O6a O 17.8102 -21.4194
23 N1a N 16.5819 -17.9200
BOND 24
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 1 5 1
6 2 6 1
7 6 7 2
8 7 8 1
9 8 9 1
10 3 9 1
11 9 10 2
12 7 11 1
13 1 12 1
14 12 13 1
15 13 14 1
16 14 15 1
17 15 16 1
18 16 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 19 21 1
23 17 22 2
24 18 23 1 #Down
|
|---|
