| Entry |
|
|---|
| Name |
Pozanicline (USAN);
ABT-089 |
|---|
| Formula |
C11H16N2O
|
|---|
| Exact mass |
192.1263
|
|---|
| Mol weight |
192.2575
|
|---|
| Structure |
|
|---|
| Class |
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Dementia therapeutic agent, Nicotinic acetylcholine receptor partial agonist |
|---|
| Comment |
Attention deficit/hyperactivity disorder, Alzheimer's type dementia
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
DG01288 Pozanicline
D09367 Pozanicline
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
Acetylcholine (nicotinic)
CHRNA4/CHRNB2
D09367 Pozanicline (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01571 Nicotinic cholinergic receptor partial agonist
DG01288 Pozanicline
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 14
1 C8y C 11.9700 -23.0300
2 C8x C 11.9700 -24.4300
3 C8x C 10.7800 -25.1300
4 C8x C 9.5200 -24.4300
5 N5x N 9.5200 -23.0300
6 C8y C 10.7800 -22.3300
7 O2a O 13.1600 -22.3300
8 C1b C 14.3500 -23.0300
9 C1y C 15.5400 -22.3300
10 C1x C 15.9600 -21.0000
11 C1x C 17.3600 -21.0000
12 C1x C 17.7800 -22.3300
13 N1x N 16.6600 -23.1700
14 C1a C 10.7800 -20.9300
BOND 15
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 1 7 1
8 7 8 1
9 9 8 1 #Down
10 10 11 1
11 11 12 1
12 12 13 1
13 13 9 1
14 10 9 1
15 6 14 1
|
|---|
