KEGG   DRUG: Ozenoxacin
Entry
D09544                      Drug                                   
Name
Ozenoxacin (JAN/USAN/INN);
Xepi (TN)
Product
XEPI (Biofrontera)
Formula
C21H21N3O3
Exact mass
363.1583
Mol weight
363.4097
Structure
Class
Antibacterial
 DG01550  Quinolone
Metabolizing enzyme substrate
 DG01633  CYP3A/CYP3A4 substrate
  DG02913  CYP3A4 substrate
Remark
Therapeutic category: 2639
ATC code: D06AX14
Product: D09544<JP/US>
Efficacy
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Quinolones
Target
DNA gyrase [KO:K02469 K02470]
topoisomerase IV [KO:K02621 K02622]
Metabolism
Enzyme: CYP3A4 [HSA:1576]
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX14 Ozenoxacin
      D09544  Ozenoxacin (JAN/USAN/INN) <JP/US>
USP drug classification [BR:br08302]
 Dermatological Agents
  Topical Anti-infectives
   Antibacterials, dermatological
    Ozenoxacin
     D09544  Ozenoxacin (JAN/USAN/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   263  Suppurative dermatosis agents
    2639  Others
     D09544  Ozenoxacin (JAN/USAN/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01550  Quinolone
   D09544  Ozenoxacin
 Metabolizing enzyme substrate
  DG01633  CYP3A/CYP3A4 substrate
   DG02913  CYP3A4 substrate
    D09544  Ozenoxacin
Antimicrobials [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   Other quinolone
    D09544  Ozenoxacin (JAN/USAN/INN) <JP/US>
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Nucleic acid synthesis inhibitor
   Other quinolone
    D09544  Ozenoxacin (JAN/USAN/INN)
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D09544
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D09544
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D09544
Drug metabolizing enzymes and transporters [br08309.html]
 Drug metabolizing enzymes
  D09544
Other DBs
CAS: 245765-41-7
PubChem: 96026224
LigandBox: D09544
LinkDB
KCF data

ATOM        27
            1   C8y C    27.6985  -22.8924
            2   C8y C    27.6985  -21.5006
            3   C8y C    28.8815  -20.8047
            4   C8y C    30.1341  -21.5006
            5   C8x C    30.1341  -22.8924
            6   N4y N    28.8815  -23.5883
            7   C8y C    26.5155  -23.5883
            8   C8y C    25.2629  -22.8924
            9   C8x C    25.2629  -21.5006
            10  C8x C    26.5155  -20.8047
            11  O5x O    28.8815  -19.4129
            12  C1y C    28.8815  -24.9800
            13  C1x C    29.5774  -26.2326
            14  C1x C    28.1856  -26.2326
            15  C6a C    31.3171  -20.8047
            16  O6a O    32.5697  -21.5006
            17  O6a O    31.3171  -19.4129
            18  C1a C    26.5155  -24.9800
            19  C8y C    24.0799  -23.5883
            20  C8x C    24.0799  -24.9800
            21  N5x N    22.8969  -25.6759
            22  C8y C    21.6443  -24.9800
            23  C8y C    21.6443  -23.5883
            24  C8x C    22.8273  -22.8924
            25  N1b N    20.4613  -25.6759
            26  C1a C    19.2087  -25.0496
            27  C1a C    20.3917  -22.8924
BOND        30
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     1   7 2
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    2  10 2
            12    3  11 2
            13    6  12 1
            14   12  13 1
            15   13  14 1
            16   14  12 1
            17    4  15 1
            18   15  16 1
            19   15  17 2
            20    7  18 1
            21    8  19 1
            22   19  20 2
            23   20  21 1
            24   21  22 2
            25   22  23 1
            26   23  24 2
            27   19  24 1
            28   22  25 1
            29   25  26 1
            30   23  27 1

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