| Entry |
|
|---|
| Name |
Tebipenem pivoxil (JAN/USAN/INN);
Orapenem (TN) |
|---|
| Formula |
C22H31N3O6S2
|
|---|
| Exact mass |
497.1654
|
|---|
| Mol weight |
497.628
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
| Therapeutic category: | 6139 |
| Product (DG03012): | D09598<JP> |
|
|---|
| Efficacy |
Antibacterial, Cell wall biosynthesis inhibitor |
|---|
| Comment |
Active form of prodrug: Tebipenem [CPD: C21522]
Treatment of severe infections
|
|---|
| Target |
penicillin binding protein |
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
J ANTIINFECTIVES FOR SYSTEMIC USE
J01 ANTIBACTERIALS FOR SYSTEMIC USE
J01D OTHER BETA-LACTAM ANTIBACTERIALS
J01DH Carbapenems
J01DH06 Tebipenem pivoxil
D09598 Tebipenem pivoxil (JAN/USAN/INN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
6 Agents against pathologic organisms and parasites
61 Antibiotics
613 Acting mainly on gram-positive and gram-negative bacteria
6139 Others
D09598 Tebipenem pivoxil (JAN/USAN/INN)
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01458 Carbapenem
DG03012 Tebipenem pivoxil
D09598 Tebipenem pivoxil
Drug classes [BR:br08332]
Antibacterial
DG01458 Carbapenem
D09598 Tebipenem pivoxil
Antimicrobials [BR:br08307]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Carbapenem
D09598 Tebipenem pivoxil (JAN/USAN/INN) <JP>
New drug approvals in Japan [br08318.html]
Drugs with new active ingredients
D09598
Prodrugs [br08324.html]
D09598
Drug groups [BR:br08330]
Antibacterial
DG01710 beta-Lactam antibiotic
DG01713 Penicillin skeleton group
DG01458 Carbapenem
DG03012 Tebipenem pivoxil
Antimicrobials abbreviations [BR:br08327]
Antibacterials
Cell wall biosynthesis inhibitor, beta-lactam
Carbapenem
DG03012 Tebipenem pivoxil
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 33
1 C1y C 19.9295 -30.4599
2 C5x C 19.9295 -31.8647
3 N1y N 21.3343 -31.8647
4 C1y C 21.3343 -30.4599
5 C2y C 22.6688 -32.2862
6 C2y C 23.5116 -31.1623
7 C1y C 22.6688 -30.0385
8 C1c C 18.7355 -29.7575
9 C1a C 17.5414 -30.4599
10 O5x O 18.7355 -32.5671
11 O1a O 18.7355 -28.3528
12 C1a C 23.0982 -28.7010
13 S2a S 24.9165 -31.1623
14 C7a C 23.0982 -33.6237
15 O7a O 24.4947 -33.6442
16 O6a O 22.2609 -34.7545
17 C1b C 25.1694 -34.8530
18 O7a O 26.6022 -34.8732
19 C7a C 27.3165 -33.6754
20 C1d C 28.7093 -33.6952
21 O6a O 26.6353 -32.4559
22 C1a C 30.1140 -33.6952
23 C1a C 28.7093 -32.2905
24 C1a C 28.7093 -35.1000
25 C1y C 25.6188 -29.9458
26 C1x C 26.9700 -29.5838
27 N1y N 26.6080 -28.2327
28 C1x C 25.2569 -28.5946
29 C2y C 27.3179 -27.0036
30 N2x N 28.7002 -26.8587
31 C1x C 28.9895 -25.4993
32 C1x C 27.7861 -24.8041
33 S2x S 26.7530 -25.7337
BOND 36
1 1 2 1
2 2 3 1
3 3 4 1
4 1 4 1
5 3 5 1
6 5 6 2
7 6 7 1
8 4 7 1
9 8 1 1
10 8 9 1
11 10 2 2
12 8 11 1 #Up
13 7 12 1 #Up
14 6 13 1
15 5 14 1
16 14 15 1
17 14 16 2
18 15 17 1
19 17 18 1
20 18 19 1
21 19 20 1
22 19 21 2
23 20 22 1
24 20 23 1
25 20 24 1
26 13 25 1
27 25 26 1
28 26 27 1
29 27 28 1
30 25 28 1
31 27 29 1
32 29 30 2
33 30 31 1
34 31 32 1
35 32 33 1
36 29 33 1
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