KEGG   DRUG: Incobotulinumtoxin A
Entry
D10012                      Drug                                   
Name
Incobotulinumtoxin A (JAN/USAN);
Onaclostox;
Xeomin (TN)
Product
XEOMIN (Merz North America), XEOMIN (Merz Pharmaceuticals)
Formula
C2286H3500N578O666S9. C4422H6863N1151O1329S23
Exact mass
148084.3667
Mol weight
148175.5251
Remark
Therapeutic category: 1229
Product: D10012<JP/US>
Efficacy
Skeletal muscle relaxant, SNAP25 protein inhibitor
  Disease
Cervical dystonia [DS:H01608]
Comment
Incobotulinumtoxin A is a botulinum toxin type A drug without complexing proteins.
Treatment of spasticty, cervical dystonia, benign essential blepharospasm and glabellar lines
Target
SNAP25 [HSA:6616] [KO:K18211]
  Pathway
hsa04721  Synaptic vesicle cycle
Interaction
Brite
USP drug classification [BR:br08302]
 Dermatological Agents
  Dermatological Agents, Other
   Dermatological Agents, Miscellaneous
    Incobotulinumtoxin A
     D10012  Incobotulinumtoxin A (JAN/USAN)
 Skeletal Muscle Relaxants
  Incobotulinum Toxin A
   D10012  Incobotulinumtoxin A (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  12  Agents affecting peripheral nervous system
   122  Skeletal muscle relaxants
    1229  Others
     D10012  Incobotulinumtoxin A (JAN/USAN)
Target-based classification of drugs [BR:br08310]
 Not elsewhere classified
  Organismal systems
   Nervous system
    SNAP25
     D10012  Incobotulinumtoxin A (JAN/USAN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D10012
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D10012
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D10012
Other DBs
CAS: 93384-43-1
PubChem: 135626733
LinkDB

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