Entry |
|
Name |
Metoprolol and hydrochlorothiazide; Dutoprol (TN); Lopressor hct (TN) |
Product |
|
Generic |
|
Component |
(Metoprolol tartrate [DR: D00601] | Metoprolol succinate [DR: D00635]), Hydrochlorothiazide [DR: D00340]
|
Class |
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
|
Remark |
|
Efficacy |
Antihypertensive |
Disease |
|
Comment |
Metoprolol is primarily metabolized by CYP2D6.
|
Metabolism |
Enzyme: CYP2D6 [HSA: 1565]
|
Interaction |
|
Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
C CARDIOVASCULAR SYSTEM
C07 BETA BLOCKING AGENTS
C07B BETA BLOCKING AGENTS AND THIAZIDES
C07BB Beta blocking agents, selective, and thiazides
C07BB02 Metoprolol and thiazides
D10273 Metoprolol and hydrochlorothiazide <US>
USP drug classification [BR:br08302]
Cardiovascular Agents
Cardiovascular Agents, Combinations
Hydrochlorothiazide/ Metoprolol Succinate
D10273 Metoprolol and hydrochlorothiazide
Hydrochlorothiazide/ Metoprolol Tartrate
D10273 Metoprolol and hydrochlorothiazide
Drug groups [BR:br08330]
Metabolizing enzyme substrate
DG01644 CYP2D6 substrate
D10273 Metoprolol and hydrochlorothiazide
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D10273
|
Other DBs |
|
LinkDB |
|