| Entry |
|
|---|
| Name |
Dasotraline hydrochloride (USAN) |
|---|
| Formula |
C16H15Cl2N. HCl
|
|---|
| Exact mass |
327.0348
|
|---|
| Mol weight |
328.6639
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
|
|---|
| Remark |
|
|---|
| Efficacy |
Noradrenalin and dopamine reuptake inhibitor |
|---|
| Comment |
Treatment of attention deficit hyperactivity disorder (ADHD)
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Brite |
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
DG01989 Dasotraline
D10870 Dasotraline hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D10870 Dasotraline hydrochloride (USAN)
SLC6A3 (DAT1)
D10870 Dasotraline hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG03059 Noradrenalin and dopamine reuptake inhibitor (NDRI)
DG01989 Dasotraline
|
|---|
| Other DBs |
|
|---|
| LinkDB |
|
|---|
| KCF data |
ATOM 20
1 C8y C 18.6957 -14.7745
2 C1y C 19.8860 -15.4747
3 C8y C 18.6957 -13.3741
4 C8x C 17.4353 -15.4747
5 C8y C 19.8860 -16.8751
6 C1x C 21.0764 -14.7745
7 C1y C 19.8860 -12.6738
8 C8x C 17.4353 -12.6738
9 C8x C 16.2449 -14.7745
10 C8x C 18.6256 -17.5753
11 C8x C 21.0764 -17.5753
12 C1x C 21.0764 -13.3741
13 C8x C 16.2449 -13.3741
14 C8y C 18.6256 -18.9757
15 C8x C 21.0764 -18.9757
16 C8y C 19.8860 -19.6760
17 X Cl 17.4353 -19.6760
18 X Cl 19.8860 -21.0764
19 N1a N 19.8860 -11.2734
20 X Cl 24.2200 -17.0100
BOND 21
1 1 2 1
2 1 3 1
3 1 4 2
4 2 5 1 #Up
5 2 6 1
6 3 7 1
7 3 8 2
8 4 9 1
9 5 10 2
10 5 11 1
11 6 12 1
12 8 13 1
13 10 14 1
14 11 15 2
15 14 16 2
16 14 17 1
17 16 18 1
18 7 12 1
19 9 13 2
20 15 16 1
21 7 19 1 #Down
|
|---|
