KEGG   DRUG: Eflapegrastim
Entry
D11188                      Drug                                   
Name
Eflapegrastim (USAN/INN);
Eflapegrastim-xnst;
Rolvedon (TN)
Product
Formula
C3070H4764N806O927S23.(C2H4O)n
Class
Immunological agent
 DG01753  Colony stimulating factor
  DG01781  Granulocyte colony stimulating factor (G-CSF)
Remark
ATC code: L03AA19
Product: D11188<US>
Efficacy
Antineutropenic, Leukocyte growth factor, Granulocyte colony stimulating factor (G-CSF)
Comment
recombinant granulocyte colony stimulating factor (G-CSF) [HSA:1440] [KO:K05423]
Reducing neutropenia and the incidence of infecton in patients with cancer
Target
CSF3R (GCSFR, CD114) [HSA:1441] [KO:K05061]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04151  PI3K-Akt signaling pathway
hsa04630  JAK-STAT signaling pathway
hsa04640  Hematopoietic cell lineage
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AA Colony stimulating factors
     L03AA19 Eflapegrastim
      D11188  Eflapegrastim (USAN/INN) <US>
USP drug classification [BR:br08302]
 Immunological Agents
  Immunostimulants
   Colony-stimulating Factors
    Eflapegrastim
     D11188  Eflapegrastim (USAN/INN)
Drug groups [BR:br08330]
 Immunological agent
  DG01753  Colony stimulating factor
   DG01781  Granulocyte colony stimulating factor (G-CSF)
    D11188  Eflapegrastim
Drug classes [BR:br08332]
 Immunological agent
  DG01753  Colony stimulating factor
   D11188  Eflapegrastim
Target-based classification of drugs [BR:br08310]
 Cytokines and receptors
  Cytokine receptors
   CSF and other factor receptors
    CSF3R (GCSFR, CD114)
     D11188  Eflapegrastim (USAN/INN) <US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11188
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11188
Other DBs
CAS: 1384099-30-2
PubChem: 384585167
LinkDB

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