KEGG   DRUG: Tirzepatide
Entry
D11360                      Drug                                   
Name
Tirzepatide (JAN/USAN);
Mounjaro (TN)
Product
Formula
C225H348N48O68
Exact mass
4810.5249
Mol weight
4813.4514
Sequence
YXEGTFTSDY SIXLDKIAQK AFVQWLIAGG PSSGAPPPS
  Type
Peptide
Class
Antidiabetic agent
 DG02044  Hypoglycemic agent
  DG01493  GLP-1 receptor agonist
Remark
Therapeutic category: 2499
ATC code: A10BX16
Product: D11360<JP/US>
Efficacy
Antidiabetic, Gastric inhibitory polypeptide receptor agonist, Glucagon-like peptide 1 (GLP-1) receptor agonist
  Disease
Type 2 diabetes mellitus [DS:H00409]
Comment
Treatment of type 2 diabetes
Target
GIPR [HSA:2696] [KO:K04580]
GLP1R [HSA:2740] [KO:K04581]
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A10 DRUGS USED IN DIABETES
   A10B BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
    A10BX Other blood glucose lowering drugs, excl. insulins
     A10BX16 Tirzepatide
      D11360  Tirzepatide (JAN/USAN) <JP/US>
USP drug classification [BR:br08302]
 Blood Glucose Regulators
  Antidiabetic Agents
   Glucose Control Agents, Other
    Tirzepatide
     D11360  Tirzepatide (JAN/USAN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D11360  Tirzepatide (JAN/USAN)
Drug groups [BR:br08330]
 Antidiabetic agent
  DG02044  Hypoglycemic agent
   DG01493  GLP-1 receptor agonist
    D11360  Tirzepatide
Drug classes [BR:br08332]
 Antidiabetic agent
  DG01493  GLP-1 receptor agonist
   D11360  Tirzepatide
  DG02044  Hypoglycemic agent
   D11360  Tirzepatide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D11360  Tirzepatide (JAN/USAN) <JP/US>
   Gastric inhibitory polypeptide
    GIPR
     D11360  Tirzepatide (JAN/USAN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11360
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D11360
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D11360
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11360
Other DBs
CAS: 2023788-19-2
PubChem: 384585338
ChEBI: 194186
LinkDB

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