KEGG   DRUG: Troriluzole hydrochloride
Entry
D11415                      Drug                                   
Name
Troriluzole hydrochloride (USAN)
Formula
C15H16F3N5O4S. HCl
Exact mass
455.0642
Mol weight
455.8398
Structure
Remark
ATC code: N07XX23
Chemical structure group: DG03011
Efficacy
Neuroprotectant
Target
GRIN (NMDAR) [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
GRIA [HSA:2890 2891 2892 2893] [KO:K05197 K05198 K05199 K05200]
GRIK [HSA:2897 2898 2899 2900 2901] [KO:K05201 K05202 K05203 K05204 K05205]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04724  Glutamatergic synapse
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07X OTHER NERVOUS SYSTEM DRUGS
    N07XX Other nervous system drugs
     N07XX23 Troriluzole
      D11415  Troriluzole hydrochloride (USAN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), non-NMDA
    GRIA
     D11415  Troriluzole hydrochloride (USAN)
    GRIK
     D11415  Troriluzole hydrochloride (USAN)
   Glutamate (ionotropic), NMDA
    GRIN (NMDAR)
     D11415  Troriluzole hydrochloride (USAN)
Other DBs
CAS: 1926204-76-3
LinkDB
KCF data

ATOM        29
            1   C1d C    10.5067  -16.1101
            2   O2a O    11.6972  -15.4098
            3   X   F     9.2462  -15.4098
            4   X   F    10.5067  -17.5107
            5   X   F     9.2462  -16.8104
            6   C8y C    12.9578  -16.1101
            7   C8x C    14.1483  -15.4098
            8   C8x C    12.9578  -17.5107
            9   C8y C    15.3388  -16.1101
            10  C8x C    14.1483  -18.2110
            11  C8y C    15.3388  -17.5107
            12  S2x S    16.6694  -15.6199
            13  N5x N    16.6694  -17.9309
            14  C8y C    17.5098  -16.7404
            15  N1b N    18.9104  -16.7404
            16  C5a C    19.6107  -17.9309
            17  C1b C    21.0113  -17.9309
            18  O5a O    18.9104  -19.1914
            19  N1c N    21.7116  -16.7404
            20  C5a C    23.1122  -16.7404
            21  C1a C    21.0113  -15.5498
            22  C1b C    23.8125  -15.5498
            23  O5a O    23.8125  -17.9309
            24  N1b N    25.2131  -15.5498
            25  C5a C    25.9134  -14.3593
            26  C1b C    27.3140  -14.3593
            27  O5a O    25.2131  -13.1688
            28  N1a N    28.0144  -13.1688
            29  X   Cl   28.7700  -19.1100
BOND        29
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     1   5 1
            5     2   6 1
            6     6   7 2
            7     6   8 1
            8     7   9 1
            9     8  10 2
            10    9  11 2
            11    9  12 1
            12   11  13 1
            13   12  14 1
            14   14  15 1
            15   10  11 1
            16   13  14 2
            17   15  16 1
            18   16  17 1
            19   16  18 2
            20   17  19 1
            21   19  20 1
            22   19  21 1
            23   20  22 1
            24   20  23 2
            25   22  24 1
            26   24  25 1
            27   25  26 1
            28   25  27 2
            29   26  28 1

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