KEGG   DRUG: Molnupiravir
Entry
D11943                      Drug                                   
Name
Molnupiravir (JAN/USAN);
Lagevrio (TN)
Product
  Other
LAGEVRIO (A-S Medication Solutions), LAGEVRIO (Merck Sharp & Dohme LLC)
Formula
C13H19N3O7
Exact mass
329.1223
Mol weight
329.3059
Structure
Class
Antiviral
 DG03174  Anti-SARS-CoV-2 agent
Remark
Therapeutic category: 6250
ATC code: J05AB18
Product: D11943<JP/US>
Efficacy
Antiviral, RNA polymerase inhibitor
  Disease
Coronavirus disease 2019 [DS:H02398]
Comment
Ribonucleoside analogue
Treatment of infections caused by RNA viral pathogens, including SARS-CoV-2
Target
SARS coronavirus replicase [KO:K24149]
  Pathway
ko03230  Viral genome structure
ko05171  Coronavirus disease - COVID-19
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AB Nucleosides and nucleotides excl. reverse transcriptase inhibitors
     J05AB18 Molnupiravir
      D11943  Molnupiravir (JAN/USAN) <JP/US>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  62  Chemotherapeutics
   625  Antivirals
    6250  Antivirals
     D11943  Molnupiravir (JAN/USAN)
Drug groups [BR:br08330]
 Antiviral
  DG03174  Anti-SARS-CoV-2 agent
   D11943  Molnupiravir
Drug classes [BR:br08332]
 Antiviral
  DG03174  Anti-SARS-CoV-2 agent
   D11943  Molnupiravir
Antimicrobials [BR:br08307]
 Antivirals
  Genome replication inhibitor
   Other inhibitor
    D11943  Molnupiravir (JAN/USAN) <JP/US>
New drug approvals in the USA [br08319.html]
 New molecular entities and new therapeutic biological products
  D11943
New drug approvals in Japan [br08318.html]
 Drugs with new active ingredients
  D11943
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D11943
Other DBs
CAS: 2492423-29-5
ChEBI: 180653
PDB-CCD: XMO[PDBj]
LinkDB
KCF data

ATOM        23
            1   C8x C    17.8926  -17.2912
            2   N4y N    17.8926  -18.6989
            3   C8y C    19.0892  -19.4028
            4   N4x N    20.3562  -18.6989
            5   C8y C    20.3562  -17.2912
            6   C8x C    19.0892  -16.5873
            7   C1y C    16.6960  -19.4028
            8   O2x O    15.4995  -18.6286
            9   C1y C    14.4437  -19.4732
            10  C1y C    14.8660  -20.7402
            11  C1y C    16.2737  -20.7402
            12  C1b C    13.2471  -18.7693
            13  O7a O    12.0505  -19.4732
            14  C7a C    10.8539  -18.7693
            15  C1c C     9.6573  -19.4732
            16  C1a C     8.4608  -18.7693
            17  C1a C     9.6573  -20.8809
            18  O6a O    10.8539  -17.3616
            19  N2b N    21.5527  -16.5873
            20  O1b O    22.8197  -17.2912
            21  O1a O    14.0213  -21.8664
            22  O1a O    17.1184  -21.8664
            23  O5x O    19.1423  -20.7895
BOND        24
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 2
            7     7   2 1 #Up
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12    7  11 1
            13    9  12 1 #Up
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   15  17 1
            19   14  18 2
            20    5  19 2
            21   19  20 1
            22   10  21 1 #Down
            23   11  22 1 #Down
            24    3  23 2

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