| Entry |
|
|---|
| Name |
Bimatoprost grenod (USAN) |
|---|
| Formula |
C31H46N2O8
|
|---|
| Exact mass |
574.3254
|
|---|
| Mol weight |
574.7055
|
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| Structure |
|
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| Class |
Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Product (DG03267): | D02724<JP/US> |
|
|---|
| Efficacy |
Antiglaucoma |
|---|
| Comment |
Treatment of glaucoma and ocular hypertension
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EE Prostaglandin analogues
S01EE03 Bimatoprost
D12599 Bimatoprost grenod (USAN)
Drug groups [BR:br08330]
Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative
DG03267 Bimatoprost
D12599 Bimatoprost grenod
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG03267 Bimatoprost
D12599 Bimatoprost grenod
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Prostaglandin
PTGFR
D12599 Bimatoprost grenod (USAN)
Drug groups [BR:br08330]
Hormonal agent
DG01961 Prostaglandin derivative
DG01960 Prostaglandin F derivative
DG03267 Bimatoprost
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG03267 Bimatoprost
|
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| Other DBs |
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| LinkDB |
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| KCF data |
ATOM 41
1 C1y C 13.5117 -15.1219
2 C1y C 13.5117 -13.7217
3 C1y C 12.1815 -13.3016
4 C1x C 11.3414 -14.4218
5 C1y C 12.1815 -15.5419
6 O1a O 11.7614 -11.9715
7 O1a O 11.7614 -16.8721
8 C1b C 14.7718 -13.0216
9 C2b C 15.9620 -13.7217
10 C2b C 14.7718 -15.8219
11 C2b C 15.9620 -15.1219
12 C1c C 17.1521 -15.8219
13 C1b C 18.4123 -15.1219
14 C1b C 19.6024 -15.8219
15 C2b C 17.3621 -13.7217
16 C1b C 18.6223 -13.0216
17 C1b C 19.8124 -13.7217
18 C1b C 21.0026 -13.0216
19 C5a C 22.2627 -13.7217
20 N1b N 23.4529 -13.0216
21 C1b C 24.6430 -13.7217
22 O7a O 17.1521 -17.2221
23 C8y C 19.6024 -17.2221
24 C8x C 18.4123 -17.9222
25 C8x C 18.4123 -19.3224
26 C8x C 19.6024 -20.0225
27 C8x C 20.7925 -19.3224
28 C8x C 20.7925 -17.9222
29 O5a O 22.2627 -15.1219
30 C1a C 25.9032 -13.0216
31 C7a C 15.9390 -17.9225
32 O6a O 14.7414 -17.2309
33 C1b C 15.9390 -19.3198
34 C1b C 14.7423 -20.0108
35 C1b C 14.7422 -21.4197
36 C1b C 13.5506 -22.1078
37 C1b C 13.5506 -23.5078
38 O2a O 12.3553 -24.1983
39 N2b N 11.1781 -23.5191 #+
40 O3a O 9.8420 -24.3503 #-
41 O3a O 11.1776 -22.1202
BOND 42
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 1
5 1 5 1
6 3 6 1 #Down
7 5 7 1 #Down
8 2 8 1 #Down
9 8 9 1
10 1 10 1 #Up
11 10 11 2
12 11 12 1
13 12 13 1
14 13 14 1
15 9 15 2
16 15 16 1
17 16 17 1
18 17 18 1
19 18 19 1
20 19 20 1
21 20 21 1
22 12 22 1 #Down
23 14 23 1
24 23 24 2
25 24 25 1
26 25 26 2
27 26 27 1
28 27 28 2
29 23 28 1
30 19 29 2
31 21 30 1
32 22 31 1
33 31 32 2
34 31 33 1
35 33 34 1
36 34 35 1
37 35 36 1
38 36 37 1
39 37 38 1
40 38 39 1
41 39 40 1
42 39 41 2
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