KEGG   DRUG: Survodutide
Entry
D12898                      Drug                                   
Name
Survodutide (USAN/INN)
Formula
C192H289N47O61
Exact mass
4229.0957
Mol weight
4231.6274
Sequence
(A chain)
HXQGTFTSDY SKYLDERAAK DFIKWLESA
(B chain)
EGSGSGG
(Amide bridge: A24-B7)
  Type
Peptide
Class
Antidiabetic agent
 DG02044  Hypoglycemic agent
  DG01493  GLP-1 receptor agonist
Efficacy
Glucagon-like peptide 1 (GLP-1) receptor agonist, Glucagon receptor agonist
Comment
Treatment of obesity and non-alcoholic steatohepatitis (NASH)
Target
GLP1R [HSA:2740] [KO:K04581]
GCGR [HSA:2642] [KO:K04583]
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04911  Insulin secretion
hsa04922  Glucagon signaling pathway
Interaction
Brite
Drug groups [BR:br08330]
 Antidiabetic agent
  DG02044  Hypoglycemic agent
   DG01493  GLP-1 receptor agonist
    D12898  Survodutide
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Secretin receptor family
   Glucagon
    GLP1R
     D12898  Survodutide (USAN/INN)
    GCGR
     D12898  Survodutide (USAN/INN)
Other DBs
CAS: 2805997-46-8
LinkDB

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