KEGG   DISEASE: Shigellosis
Entry
H00299                      Disease                                
Name
Shigellosis;
Bacillary dysentery
Description
Shigellosis (bacillary dysentery) is a foodborne enterobacterial infection caused by Shigella species. There are four subgroups of Shigella: S. dysenteriae, S. flexneri, S. boydii, and S. sonnei. Of these, S. flexneri is the most frequently observed worldwide, and S. dysenteriae causes severe disease with the highest fatality rate. Transmission usually occurs via contaminated food and water or through person-to-person contact.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Gastroenteritis or colitis of infectious origin
   Bacterial intestinal infections
    1A02  Intestinal infections due to Shigella
     H00299  Shigellosis
Pathway-based classification of diseases [BR:br08402]
 Signal transduction
  nt06516  TNF signaling
   H00299  Shigellosis
 Cellular process
  nt06532  Autophagy
   H00299  Shigellosis
  nt06524  Apoptosis
   H00299  Shigellosis
 Immune system
  nt06517  TLR signaling
   H00299  Shigellosis
  nt06521  NLR signaling
   H00299  Shigellosis
  nt06520  CGAS-STING signaling
   H00299  Shigellosis
Genome-based classification of infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by enterobacteria
   H00299  Shigellosis
Disease
pathway
hsa05131  Shigellosis
Network
nt06182 Shigella
nt06516 TNF signaling
nt06517 TLR signaling
nt06520 CGAS-STING signaling
nt06521 NLR signaling
nt06524 Apoptosis
nt06532 Autophagy
Pathogen
Shigella flexneri [GN:sfl sfx sfv sfe sft]
Shigella sonnei [GN:ssn]
Shigella boydii [GN:sbo sbc]
Shigella dysenteriae [GN:sdy sdz]
shiga toxin [KO:K11006 K11007]
enterotoxin ShET-1 [KO:K11011 K11012]
Drug
Co-Trimoxazole [DR:D00285]
Other DBs
ICD-11: 1A02
ICD-10: A03
MeSH: D004405
MedlinePlus: 000295
Reference
  Authors
Kweon MN
  Title
Shigellosis: the current status of vaccine development.
  Journal
Curr Opin Infect Dis 21:313-8 (2008)
DOI:10.1097/QCO.0b013e3282f88b92
Reference
  Authors
Warren BR, Parish ME, Schneider KR
  Title
Shigella as a foodborne pathogen and current methods for detection in food.
  Journal
Crit Rev Food Sci Nutr 46:551-67 (2006)
DOI:10.1080/10408390500295458
Reference
  Authors
Niyogi SK
  Title
Shigellosis.
  Journal
J Microbiol 43:133-43 (2005)
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