KEGG   DISEASE: Rabies
Entry
H00377                      Disease                                
Name
Rabies
Description
Rabies is a typical zoonotic disease caused by rabies virus that belongs to the genus Lyssavirus, within the family Rhabdoviridae and the order Mononegavirales of -ssRNA viruses. Dogs are the major vectors. Rabies affects the central nervous system and causes fatal encephalomyelitis.
Category
Viral infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 01 Certain infectious or parasitic diseases
  Viral infections of the central nervous system
   1C82  Rabies
    H00377  Rabies
Genome-based classification of infectious diseases [BR:br08401]
 Viral infections
  Infections caused by -ssRNA viruses
   H00377  Rabies
Pathogen
Rabies virus (RABV) [GN:T40022]
Drug
Rabies vaccine [DR:D06504]
Comment
Preexposure vaccination with modern cell culture vaccine is recommended for people at high risk of exposure. Postexposure prophylaxis consists of wound cleansing and immunization with modern cell culture vaccine, together with administration of rabies immune globulin. There is no certain cure for rabies except supportive care.
Other DBs
ICD-11: 1C82
ICD-10: A82
MeSH: D011818
MedlinePlus: 001334
Reference
  Authors
Yousaf MZ, Qasim M, Zia S, Khan Mu, Ashfaq UA, Khan S
  Title
Rabies molecular virology, diagnosis, prevention and treatment.
  Journal
Virol J 9:50 (2012)
DOI:10.1186/1743-422X-9-50
Reference
  Authors
Takayama N
  Title
Rabies: a preventable but incurable disease.
  Journal
J Infect Chemother 14:8-14 (2008)
DOI:10.1007/s10156-007-0573-0
Reference
  Authors
Leung AK, Davies HD, Hon KL
  Title
Rabies: epidemiology, pathogenesis, and prophylaxis.
  Journal
Adv Ther 24:1340-7 (2007)
DOI:10.1007/BF02877781
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