Pseudomonas aeruginosa is a leading cause of nosocomial bloodstream infections, ranking third among gram-negative bacteria, after Escherichia coli and Klebsiella species. Intrinsic resistance has been traditionally attributed to the low permeability of cellular envelopes together with the presence of chromosomally-encoded detoxification systems such as multidrug efflux pumps or antibiotic inactivating enzymes. Some strains acquire increased resistance via the horizontal transfer of resistance determinants and mutations in chromosomal genes.
Category
Bacterial infectious disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
01 Certain infectious or parasitic diseases
Other bacterial diseases
1C41 Bacterial infection of unspecified site
H01441 Pseudomonas aeruginosa infection
12 Diseases of the respiratory system
Lung infections
CA40 Pneumonia
H01441 Pseudomonas aeruginosa infection
Genome-based classification of infectious diseases [BR:br08401]
Bacterial infections
Infections caused by other gamma proteobacteria
H01441 Pseudomonas aeruginosa infection
