KEGG   DISEASE: Interstitial cystitis
Entry
H01551                      Disease                                
Name
Interstitial cystitis;
Bladder pain syndrome
Description
Interstitial cystitis (IC), also referred to as bladder pain syndrome (BPS), is a chronic non-infectious inflammatory condition characterized by recurring discomfort, pain or pressure in the bladder and the surrounding pelvic region. IC/BPS most often affect females compared with males. The affected individuals experience urinary frequency and urgency. The duration of irritative symptoms associated with unpleasant sensation are longer than six weeks duration. At present, there are two major subtypes of IC/BPS: those with or without Hunner lesion, which are also known as ulcerative or non-ulcerative IC/BPS, respectively.
Category
Urinary system disease
Brite
Human diseases in ICD-11 classification [BR:br08403]
 16 Diseases of the genitourinary system
  Diseases of the urinary system
   Certain specified diseases of urinary system
    GC00  Cystitis
     H01551  Interstitial cystitis
Drug
Pentosan polysulfate sodium [DR:D05428]
Dimethyl sulfoxide [DR:D01043]
Other DBs
ICD-11: GC00.3
ICD-10: N30.1
MeSH: D018856
Reference
  Authors
Ogawa T, Ishizuka O, Ueda T, Tyagi P, Chancellor MB, Yoshimura N
  Title
Current and emerging drugs for interstitial cystitis/bladder pain syndrome (IC/BPS).
  Journal
Expert Opin Emerg Drugs 20:555-70 (2015)
DOI:10.1517/14728214.2015.1105216
Reference
  Authors
Barbalias GA, Liatsikos EN, Athanasopoulos A, Nikiforidis G
  Title
Interstitial cystitis: bladder training with intravesical oxybutynin.
  Journal
J Urol 163:1818-22 (2000)
DOI:10.1016/S0022-5347(05)67551-9
Reference
  Authors
Taneja R, Jawade KK
  Title
A rational combination of intravesical and systemic agents for the treatment of interstitial cystitis.
  Journal
Scand J Urol Nephrol 41:511-5 (2007)
DOI:10.1080/00365590701435918
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