KEGG DISEASE: Soft tissue sarcomas

DISEASE: Soft tissue sarcomas

Entry

H02427                      Disease

Name

Soft tissue sarcomas

Subgroup

Fibrosarcoma
Rhabdomyosarcoma [DS:H00037]
Leiomyosarcoma
Well-differentiated liposarcoma
Myxoid liposarcoma [DS:H00049]
Round-cell liposarcoma
Pleomorphic liposarcoma
Hemangiosarcoma
Epithelioid hemangiosarcoma
Kaposi sarcoma [DS:H00041]
Neurofibrosarcoma
Malignant peripheral nerve sheath tumor
Synovial sarcoma [DS:H00050]
Extraskeletal osteosarcoma
Extraskeletal myxoid chondrosarcoma [DS:H00053]
Ewing sarcoma [DS:H00035]
Alveolar soft part sarcoma [DS:H00051]
Epithelioid sarcoma
Clear cell sarcoma of soft tissue [DS:H00052]
Angiosarcoma [DS:H01666]
Undifferentiated high-grade pleomorphic sarcoma

Description

Soft-tissue sarcomas (STS) are a rare and heterogeneous group of tumors with mesenchymal origin, including muscle, endothelium, cartilage. Several common STSs have harbored translocations, which represent clinical targets. In addition to translocations, other genomic changes and epigenetic mechanisms have been shown to be involved in the histogenesis of STS.

Category

Cancer

Brite

Human diseases in ICD-11 classification [BR:br08403]
02 Neoplasms
  Malignant neoplasms, except primary neoplasms of lymphoid, haematopoietic, central nervous system or related tissues
   Malignant neoplasms, stated or presumed to be primary, of specified sites, except of lymphoid, haematopoietic, central nervous system or related tissues
    Malignant mesenchymal neoplasms
     2B55  Rhabdomyosarcoma, primary site
      H02427  Soft tissue sarcomas
     2B5A  Synovial sarcoma, primary site
      H02427  Soft tissue sarcomas

Drug

Trabectedin [DR:D06199]
Doxorubicin hydrochloride [DR:D01275]
Pazopanib hydrochloride [DR:D05380]
Olaratumab [DR:D09939]
Eribulin mesylate [DR:D08914]
Tazemetostat hydrobromide [DR:D11485]

Other DBs

ICD-11:

2B55 2B5A

ICD-10:

C22.3 C46.1

MeSH:

D012509

Reference

PMID:29416168

Authors

Vodanovich DA, M Choong PF

Title