| Entry |
|
|---|
| Name |
Amplified AR to androgen receptor signaling pathway
|
|---|
| Definition |
(T,DHT) -> AR* => KLK3 |
|---|
| Expanded |
(C00535,C03917) -> 367v1 => 354 |
|---|
| Class |
|
|---|
| Type |
Variant
|
|---|
| Pathway |
|
|---|
| Disease |
|
|---|
| Gene |
| 367 | AR; androgen receptor |
| 354 | KLK3; kallikrein related peptidase 3 |
|
|---|
| Variant |
367v1 (AR*) AR amplification
|
|---|
| Metabolite |
|
|---|
| Reference |
|
|---|
| Authors |
Nelson WG, De Marzo AM, Isaacs WB. |
|---|
| Title |
Prostate cancer. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Culig Z, Hobisch A, Cronauer MV, Cato AC, Hittmair A, Radmayr C, Eberle J, Bartsch G, Klocker H |
|---|
| Title |
Mutant androgen receptor detected in an advanced-stage prostatic carcinoma is activated by adrenal androgens and progesterone. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Pienta KJ, Bradley D. |
|---|
| Title |
Mechanisms underlying the development of androgen-independent prostate cancer. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Feldman BJ, Feldman D. |
|---|
| Title |
The development of androgen-independent prostate cancer. |
|---|
| Journal |
|
|---|
| Reference |
|
|---|
| Authors |
Koivisto P, Kolmer M, Visakorpi T, Kallioniemi OP. |
|---|
| Title |
Androgen receptor gene and hormonal therapy failure of prostate cancer. |
|---|
| Journal |
Am J Pathol 152:1-9 (1998) |
|---|
| LinkDB |
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