| Entry |
|
|---|
| Name |
AML1-ETO fusion to PU.1-mediated transcription
|
|---|
| Definition |
AML1-ETO -| SPI1 => (CD14,ITGAM,FCGR1A) |
|---|
| Expanded |
861v2 -| 6688 => (929,3684,2209) |
|---|
| Class |
|
|---|
| Type |
Variant
|
|---|
| Pathway |
|
|---|
| Disease |
|
|---|
| Gene |
| 861 | RUNX1; runt related transcription factor 1 |
| 6688 | SPI1; Spi-1 proto-oncogene |
| 3684 | ITGAM; integrin subunit alpha M |
| 2209 | FCGR1A; Fc fragment of IgG receptor Ia |
|
|---|
| Variant |
861v2 (AML1-ETO) AML1-ETO fusion
|
|---|
| Reference |
|
|---|
| Authors |
Vangala RK, Heiss-Neumann MS, Rangatia JS, Singh SM, Schoch C, Tenen DG, Hiddemann W, Behre G |
|---|
| Title |
The myeloid master regulator transcription factor PU.1 is inactivated by AML1-ETO in t(8;21) myeloid leukemia. |
|---|
| Journal |
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|---|
| LinkDB |
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