Entry |
|
Name |
KSHV vGPCR to GNB/G-PI3K-AKT signaling pathway
|
Definition |
vGPCR -> GNB/G |
Expanded |
K21667 -> (2782,2783,2784,59345,10681,54331,2785,2786,2787,2788,94235,2790,2791,55970,51764,2792,2793) |
Class |
nt06224 CXCR signaling (cancer)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
|
Type |
Pathogen
|
Pathway |
hsa05167 | Kaposi sarcoma-associated herpesvirus infection |
|
Disease |
|
Gene |
2782 | GNB1; G protein subunit beta 1 |
2783 | GNB2; G protein subunit beta 2 |
2784 | GNB3; G protein subunit beta 3 |
59345 | GNB4; G protein subunit beta 4 |
10681 | GNB5; G protein subunit beta 5 |
54331 | GNG2; G protein subunit gamma 2 |
2785 | GNG3; G protein subunit gamma 3 |
2786 | GNG4; G protein subunit gamma 4 |
2787 | GNG5; G protein subunit gamma 5 |
2788 | GNG7; G protein subunit gamma 7 |
94235 | GNG8; G protein subunit gamma 8 |
2790 | GNG10; G protein subunit gamma 10 |
2791 | GNG11; G protein subunit gamma 11 |
55970 | GNG12; G protein subunit gamma 12 |
51764 | GNG13; G protein subunit gamma 13 |
2792 | GNGT1; G protein subunit gamma transducin 1 |
2793 | GNGT2; G protein subunit gamma transducin 2 |
|
Perturbant |
K21667 (vGPCR) | vGPCR; KSHV G-protein coupled receptor |
|
Reference |
|
Authors |
Mesri EA, Cesarman E, Boshoff C |
Title |
Kaposi's sarcoma and its associated herpesvirus. |
Journal |
|
Reference |
|
Authors |
Montaner S |
Title |
Akt/TSC/mTOR activation by the KSHV G protein-coupled receptor: emerging insights into the molecular oncogenesis and treatment of Kaposi's sarcoma. |
Journal |
|
Reference |
|
Authors |
O'Hayre M, Degese MS, Gutkind JS |
Title |
Novel insights into G protein and G protein-coupled receptor signaling in cancer. |
Journal |
|
Reference |
|
Authors |
Abere B, Schulz TF |
Title |
KSHV non-structural membrane proteins involved in the activation of intracellular signaling pathways and the pathogenesis of Kaposi's sarcoma. |
Journal |
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LinkDB |
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