KEGG   NETWORK: N00165
Entry
N00165                      Network                                
Name
KSHV vIAP to crosstalk between extrinsic and intrinsic apoptotic pathways
Definition
vIAP -| CASP3
  Expanded
K21661 -| 836
Class
nt06524 Apoptosis
nt06231 Apoptosis (cancer)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
Type
Pathogen
Pathway
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Disease
H00041  Kaposi sarcoma
Gene
836  CASP3; caspase 3
Perturbant
K21661 (vIAP)  vIAP; KSHV inhibitor of apoptosis protein
Reference
  Authors
Liang C, Lee JS, Jung JU
  Title
Immune evasion in Kaposi's sarcoma-associated herpes virus associated oncogenesis.
  Journal
Semin Cancer Biol 18:423-36 (2008)
DOI:10.1016/j.semcancer.2008.09.003
Reference
  Authors
Wang HW, Sharp TV, Koumi A, Koentges G, Boshoff C
  Title
Characterization of an anti-apoptotic glycoprotein encoded by Kaposi's sarcoma-associated herpesvirus which resembles a spliced variant of human survivin.
  Journal
EMBO J 21:2602-15 (2002)
DOI:10.1093/emboj/21.11.2602
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