KEGG   NETWORK: N00169
Entry
N00169                      Network                                
Name
KSHV LANA to p21-cell cycle G1/S
Definition
LANA -| TP53
  Expanded
K21664 -| 7157
Class
nt06230 Cell cycle (cancer)
nt06164 Kaposi sarcoma-associated herpesvirus (KSHV)
Type
Pathogen
Pathway
hsa05167  Kaposi sarcoma-associated herpesvirus infection
Disease
H00041  Kaposi sarcoma
Gene
7157  TP53; tumor protein p53
Perturbant
K21664 (LANA)  vLANA; KSHV latency-associated nuclear antigen
Reference
  Authors
Schulz TF
  Title
Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8): epidemiology and pathogenesis.
  Journal
J Antimicrob Chemother 45 Suppl T3:15-27 (2000)
DOI:10.1093/jac/45.suppl_4.15
Reference
  Authors
Cai Q, Verma SC, Lu J, Robertson ES
  Title
Molecular biology of Kaposi's sarcoma-associated herpesvirus and related oncogenesis.
  Journal
Adv Virus Res 78:87-142 (2010)
DOI:10.1016/B978-0-12-385032-4.00003-3
Reference
  Authors
Direkze S, Laman H
  Title
Regulation of growth signalling and cell cycle by Kaposi's sarcoma-associated herpesvirus genes.
  Journal
Int J Exp Pathol 85:305-19 (2004)
DOI:10.1111/j.0959-9673.2004.00407.x
Reference
  Authors
Mesri EA, Cesarman E, Boshoff C
  Title
Kaposi's sarcoma and its associated herpesvirus.
  Journal
Nat Rev Cancer 10:707-19 (2010)
DOI:10.1038/nrc2888
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