Entry Name Nuclear-initiated estrogen signaling pathway
Definition E2 -> ((ESR1/2)+(NCOA1/2/3)) => (BCL2,EBAG9,KRT19,CTSD,TFF1,PGR)
Expanded C00951 -> ((2099,2100)+(8648,10499,8202)) => (596,9166,3880,1509,7031,5241)
Class Type Reference
Pathway Gene 2099 ESR1; estrogen receptor 1
2100 ESR2; estrogen receptor 2
8648 NCOA1; nuclear receptor coactivator 1
10499 NCOA2; nuclear receptor coactivator 2
8202 NCOA3; nuclear receptor coactivator 3
596 BCL2; BCL2, apoptosis regulator
9166 EBAG9; estrogen receptor binding site associated, antigen, 9
7031 TFF1; trefoil factor 1
5241 PGR; progesterone receptor
Metabolite Reference Authors Ascenzi P, Bocedi A, Marino M
Title Structure-function relationship of estrogen receptor alpha and beta: impact on human health.
Journal Reference Authors Egeland NG, Lunde S, Jonsdottir K, Lende TH, Cronin-Fenton D, Gilje B, Janssen EA, Soiland H
Title The Role of MicroRNAs as Predictors of Response to Tamoxifen Treatment in Breast Cancer Patients.
Journal Reference Authors McDonnell DP, Norris JD
Title Connections and regulation of the human estrogen receptor.
Journal Reference Authors Welboren WJ, Sweep FC, Span PN, Stunnenberg HG
Title Genomic actions of estrogen receptor alpha: what are the targets and how are they regulated?
Journal Reference Authors Carroll JS, Meyer CA, Song J, Li W, Geistlinger TR, Eeckhoute J, Brodsky AS, Keeton EK, Fertuck KC, Hall GF, Wang Q, Bekiranov S, Sementchenko V, Fox EA, Silver PA, Gingeras TR, Liu XS, Brown M
Title Genome-wide analysis of estrogen receptor binding sites.
Journal Reference Authors O'Lone R, Frith MC, Karlsson EK, Hansen U
Title Genomic targets of nuclear estrogen receptors.
Journal LinkDB All DBs
